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Updated: June 9, 2025
I have succeeded in splitting up "heavy daturine" by two different methods. By recrystallizing the gold salt six times from boiling water, the salt of hyoscyamine, which melts at from 316 deg. F. to 323 deg. F., crystallizes our first, and by the successive evaporation of the mother liquor at last obtain the pure gold salt of atropine, which melts at 275 deg. F. to 280 deg.
'Good God! what with? 'Atropine. 'Good Heavens! 'Don't be frightened: I think he will recover. 'Is that certain? 'Yes, I think that is, if he leaves off taking the drug, Wilson. 'What! it is he who has poisoned himself? I hesitated, I hesitated. But I said: 'He is in the habit of taking atropine, Wilson.
=Calabar Bean or Physostigma.= The bean of Physostigma venenosum contains the alkaloid physostigmine or eserine, with the antagonistic alkaloid calabarine. Symptoms. Vomiting, giddiness, irregular cardiac action, contraction of the pupils, paralysis of lower extremities, and death from asphyxia. Treatment. Emetics; hypodermic injection of 1/50 grain sulphate of atropine, repeated if necessary.
"What did you take it to be, then? Jam? Two grains of atropine will cause death." For answer she clung to my knees. I released myself, and moved away a few steps. She jumped up, and made a dash for the door, but I happened to have locked it. "Where is Madame Deschamps?" I asked. "She returns to Paris to-morrow. Monsieur will let me go. I was only a tool."
Poison-hemlock is common on waysides and waste places in New York, West Virginia, Pennsylvania, New Jersey, and Ohio. It is also found in New England and Michigan, Wisconsin, Illinois, Louisiana, and California. The treatment recommended by professionals is emetics, warmth of hands and feet, artificial respiration, and the subcutaneous injection of atropine, administered by a physician.
Add to that two months of dieting in cell 24; exercises repeated a thousand times to enable me to hold my features in a certain grimace, to carry my head at a certain inclination, and adapt my back and shoulders to a stooping posture. Then five drops of atropine in the eyes to make them haggard and wild, and the trick is done." "I do not understand how you deceived the guards."
It is true that Schmidt had received pure atropine under the name of daturine, for I have proved most conclusively that the so-called daturine supplied by Trommsdorff, of Erfurt, is pure atropine and nothing else. It has no action whatever on polarized light. Discovered by Geiger and Hesse in 1833. It was first obtained in the form of needles, which were much more soluble than atropine.
According to the early researches we could not discover any of these relationships which only become evident when we come to study the new discoveries which have been made in connection with the tropines, to which class belong both duboisine and hyoscyamine, which, although differing from atropine, are equally mydriatic in their action. Discovered by Mein in 1831 in the roots of belladonna.
New unpublished researches into this problem have shown that it closely resembles neurine, a body which I hope will speedily lead us to the complete synthesis of atropine. The fusing point of atropine is not 194 deg. F., as stated by Planta, but 237 deg. F. Crystallized from not too dilute alcohol it forms crystals which are aggregations of prisms.
At present, I want to dilate his eyes with atropine, so that he may see weird shapes and be tortured of ghouls." "Poor devil! He won't need atropine for that." "Don't believe it, James. In some respects he's cold-blooded as a fish. Besides, he carries bromide tablets for his own use. He simply couldn't have arranged beforehand to dope us." "He's getting scared."
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