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Updated: June 9, 2025
The power of accommodation is lost after the application of atropine, in consequence, as is supposed, of the paralysis of this muscle. This, I believe, is the nearest approach to a demonstration we have on this point.
The formation of a series of alkaloids under the name of codeines, by the substitution of other organic radicals instead of methyl in the codeine reaction, has already been alluded to. Atropine can be formed by uniting tropine and tropic acid, the two decomposition products already noted.
Ether from the acid solution dissolves out colchicin, digitalin, cantharidin, and picrotoxin, and traces of veratrine and atropine. Separate the ethereal solution and evaporate. Hot water will now dissolve out picrotoxin, colchicin, and digitalin, but not cantharidin.
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