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Updated: April 30, 2025


Just as all the preparations were completed, there came a loud knock at the door; and the Schoolmaster himself appeared, his clothes torn, one flap off his hat, a bandage covering his right eye, leading in a little crowd of scholars that he had collected with infinite toil from many perilous positions. There were two Hedgehogs, a young Fox, five Badgers, a Mole, and a tame Guinea-pig.

By a stern necessity of fate, which no one regrets more keenly than the laboratory workers themselves, the guinea-pig has had to be used as a stepping-stone for every inch of this progress.

"Grown out of knowledge! Eightpence halfpenny you owe me now. I had to put on another farthing a week because his appetite grew so big. I knew you would rather pay more than see him suffer. And the guinea-pig died. There's twopence extra for funeral expenses. We put him in the orchard beside the dogs, and made a headstone out of your old slate.

Instantly attention was turned in this direction, and it was quickly found that if a guinea-pig were injected with a very small dose of the diphtheria toxin and allowed to recover, he would then be able to throw off a still larger dose, until finally, after a number of weeks, he could be given a dose which would have promptly killed him in the beginning of the experiments, but which he now readily resisted and recovered from.

Several centuries of guinea-pig time went by; generation after generation of healthy guinea-pigs passed under his modifying hands; and after some five years he had in one small yard a fine group of the descendants of his gall-fed pair, and in another the offspring of the trained ones; nimble, swift, as different from the first as the razor-backed pig of the forest from the fatted porkers in the sty.

Brown-Séquard's discovery that an epileptic tendency artificially produced by mutilating the nervous system of a guinea-pig is occasionally inherited may be a fact of "considerable weight," or on the other hand it may be entirely irrelevant. Cases of this kind strike one as peculiar exceptions rather than as examples of a general rule or law.

That a squirrel or a meadow-lark, or even a guinea-pig, is just as wild as the wild beasts in a travelling circus is outside the comprehension of the vulgar, who really hunger after mere marvels, whatever they may be, and actually have no eyes for beauty at all.

Agnostic and Churchman, denier and believer, have split on the same amatory rock. The knowledge breathes no sympathy in the Dop Doctor. He observes the Chaplain's face, dispassionately and yet intently, as in the old Hospital days he might have studied the expression of a monkey or a guinea-pig, or other organism upon which he was experimenting with some new drug.

This literary effort he carefully dispatched by a Guinea-pig to its destination, and awaited a reply with the utmost impatience. The reply was laconic, but highly satisfactory. It was a verbal one, given by Oliver himself in class that afternoon, who volunteered the information to the delighted Bullinger that it was a "jolly day." It was indeed a jolly day to that contrite youth.

His friends made interest for him in the requisite quarters, and Harry was soon embarked for Bombay, as a midshipman in the East India service; in which office he was known as a "guinea-pig," a humorous appellation then bestowed upon the middies of the Company.

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