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Updated: May 16, 2025
M. Plantat proceeded: "So Doctor Gendron has been applied to. He has, as you know, found reactive drugs which betray the presence of an alkaloid, whatever it may be, in the substances submitted to him for analysis. He has spoken to me of a certain sensitive paper " Appealing to all his energy, Robelot forced himself to stand up and resume a calm countenance.
"I had expected to find a poison, perhaps an alkaloid," he continued slowly, as he outlined his discoveries by the use of one of the most fascinating branches of modern science, spectroscopy. "In cases of poisoning by these substances, the spectroscope often has obvious advantages over chemical methods, for minute amounts will produce a well-defined spectrum.
He had been shot down with an ammonia gun, and the powerful alkaloid gas had almost killed him. For a long time he breathed in gasps, but his splendid constitution pulled him through. When they saw that he was recovering, the two men left the room, after examining the iron-barred windows, and as they went out they locked and barred the door behind them.
Nicotianin, or the volatile oil, is probably the odorous principle of tobacco. According to some, it does not exist in the fresh leaves, but is generated in the drying process. When obtained by distillation, a pound of leaves will yield only two grains; it is therefore in a much smaller proportion than the alkaloid, forming only one half of one per cent.
"YOUR family, perhaps." Faraday Little smiled in the superiority of boyhood over girlhood. "I allude to the classification. That plant is the belladonna, or deadly nightshade. Its alkaloid is a narcotic poison." Sauciness turned pale. "I have just eaten some!" And began to whimper. "O dear, what shall I do?" Then did it, i. e. wrung her small fingers and cried. "Pardon me one moment."
"What do you think it is?" I asked, unable to restrain myself. "Aconite," he answered slowly, "of which the active principle is the deadly poisonous alkaloid, aconitin."
Stone made himself comfortable in a near-by chair. "Aconitine is the alkaloid of aconite. I believe that in India it is frequently employed, not only for the destruction of wild beasts, but for criminal purposes. The India variety is known as the Bish poison." Kent started Bish poison was he never to get away from the letter "B"? "Can you procure Bish in this country?" he asked.
As the toxins are gradually eliminated from the body the symptoms abate, and if no more are introduced they disappear. Sapræmia in these respects, therefore, is comparable to poisoning by any other form of alkaloid, such as strychnin or morphin.
Many years ago scientists analyzed its poisonous alkaloids and found what they called bulbosine. Later it was named muscarin, and now is sometimes known as amanitin, since it is confined to the mushrooms of the Amanita genus. "Amanitin is a wonderful and dangerous alkaloid, which is absorbed in the intestinal canal. It is extremely violent.
"A popular but inexcusable error," said the doctor. "It is the tarry by-products of tobacco which cause that stain. Nicotine itself, of course, is a volatile alkaloid base of which there is only the merest trace in tobacco. It is one of the deadliest of nerve poisons and is quite colourless. There is enough of that stain upon your fingers if it were nicotine to kill a dozen men."
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