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Updated: May 5, 2025


He paused a moment, as if in deference to my inability to follow him on such an abstruse topic, then resumed, "As far as I am able to determine, this poison or toxin is an amin similar to that secreted by certain cephalopods found in the neighborhood of Naples. It is an aromatic amin. Smell it." I bent over and inhaled the peculiar odor.

Good general elimination by catharsis, warm baths to increase the peripheral circulation, a low diet for a few days, abstinence from any toxin which could cause this cardiac irritation, extra physical and mental rest, sometimes nervous sedatives such as bromids, and perhaps a lowering of the blood pressure by nitroglycerin, if such is indicated, or an increase of the cardiac tone by digitalis if that is indicated, will generally remove the cardiac irritation and prevent the extrasystoles, and the heart will again become regular.

Guinea-pigs fed on them in proper doses attain such a degree of immunity that, in a short time, they can tolerate four hundred times the fatal dose. The serum also can be used to neutralize the toxin in another animal, to a certain extent." We crowded about Kennedy and the doctor, our eyes riveted on the drawn face before us. Would the antitoxin work?

It has been shown that when artificially injected into animals in large amounts the fatigue toxin causes death. The fatigue toxin in normal quantities is said to be counteracted by an antidote or antitoxin, also generated in the body. But as soon as fatigue becomes abnormal the antitoxin is not produced fast enough to counteract the poison of the toxin."

On the other hand, fear, hate, and all forms of unkindness evolve a toxin, katabolism, which tends to clog circulation, disturb digestion, congest the secretions and stupefy the senses; and it tends to the dissolution and destruction of life. All that saddens, embitters and disappoints produces this chemical change that makes for death.

If the resemblance amounted to identity, we would have to admit that a specific toxin may produce a specific mental reaction which we have concluded on other grounds to be psychogenic. As a matter of fact, in two particulars these reactions show relationship to organic delirium.

Before, however, it has thickened in more than occasional spots or patches, the toxin has begun to penetrate into the blood, and the little patient will complain of headache, feverishness, and backache, often indeed, usually before any very marked soreness in the throat is complained of.

It is as simple to learn how to use crotalin or botulin toxin or any number of hundreds of deadly substances as it is to obtain the majority of them. In fact, if people generally understood the ease with which whole communities could be wiped out, and grasped that it could be done so as to leave virtually no clue to the author of the horror, they might not sleep as soundly at night as they do.

The infection is for all practical purposes a local one, the symptoms of the disease being due to the toxins produced in the wound of infection acting upon the central nervous system. The toxin acts principally on the nerve centres in the spinal medulla, to which it travels from the focus of infection by way of the nerve fibres supplying the voluntary muscles.

Groups of rabbits were gently kept awake for one hundred hours by relays of students, an experiment which steadily withdrew energy but caused not the slightest physical or emotional injury to any of them; no drug, toxin, or other agent was given to them; they were given sufficient food and drink.

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