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Updated: May 5, 2025
"On the other hand, the few drops of toxin in the glass possessed every advantage from the unknown's standpoint. It was invisible, and as sure in its action as the venom. Also it was as rare and as difficult to trace. For, remember this. Botulism is food poisoning.
Upon that circumstance they might, had it sorted with their inclinations, have set up a stronger case of poisoning against Charles than against the Pope, and they would not have been put to the necessity of inventing a toxin that never had place in any earthly pharmacopoeia. It is not, by this, suggested that there is any shadow of a case against Charles.
"It's done me harm," cried Aaron fretfully. "Send me to the hospital, or you'll repent it. Get rid of me in time." "Nay," said Lilly. "You get better. Damn it, you're only one among a million." Again over Aaron's face went the ghastly grimace of self-repulsion. "My soul's gone rotten," he said. "No," said Lilly. "Only toxin in the blood."
The clinical features vary in the different varieties of moist gangrene, but the local results of bacterial action and the constitutional disturbance associated with toxin absorption are present in all; the prognosis therefore is grave in the extreme.
If the irregularity is caused by toxins, the treatment is to stop the ingestion of the toxin and to promote the elimination of what is already in the system; how much of the irregularity was due to the toxin and how much is inherent disturbance in the heart can then be determined.
"As a matter of fact, the use of that drug is not less clever than the use of the venom or the toxin; it is more so. Stop and think a minute! The snake venom was employed in the case of Miss Lamar's death because it offered about the least possible chance of leaving telltale clues behind.
Collapse often follows upon shock for example, in intestinal perforations, or after abdominal operations complicated by peritonitis, especially if there is vomiting, as in cases of obstruction high up in the intestine. The symptoms of collapse are aggravated if toxin absorption is superadded to the loss of fluid.
"Your father! But he died of typhoid fever you know that as well as I do; there was nothing wrong about it." "They gave him typhoid fever, by means of culture in the milk he was taking. When he was getting well, Sartorius brought on a relapse by means of injecting the pure toxin, deadly stuff. The old man hadn't the ghost of a chance.
"Medical Science has demonstrated," says this most important paragraph, "that while fatigue is a normal phenomenon ... excessive fatigue or exhaustion is abnormal.... It has discovered that fatigue is due not only to actual poisoning, but to a specific poison or toxin of fatigue, entirely analogous in chemical and physical nature to other bacterial toxins, such as the diphtheria toxin.
These effects of the diphtheria toxin are also of interest for a somewhat unexpected reason, since it has been claimed that they are effects of the antitoxin, by those who are opposed to its use.
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