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Updated: May 20, 2025
This fact, together with a number of others, make clear that while the gonads may be the jeune premier of the drama, the vitality of the plot depends upon the other endocrines. Since old age is an exhaustion, permanent and irreparable of all the members of the ductless gland directorate, the reason becomes clear for the temporary quality of the rejuvenation effected by the procedures of Steinach.
The significance of these cyclic changes has been tremendously increased by the recent formal admission of women to participation in public activities on a plane of equality with men. Evidence exists that in man, too, there is some cyclic rhythmicity of his endocrines, which sets up a fluctuation in his physical and mental efficiency.
The ova, the female egg cells, are the fundamental concern of the ovary. Secondarily, it secretes its messengers to keep the rest of the body, and particularly the other endocrines, in touch with the necessities of the adventures of these ova. It is thus enabled to bend every force and power at its command to the service of the reproductive instinct.
With the proper dosage of the gland substance the patient remains normal; with too little she becomes dull and stupid; with too much she becomes unstable and emotional! There are plenty of other examples of the influence of the endocrines on mind, character and personality. I here briefly mention a few of these.
Rapid decay of the teeth in childhood should always call attention to the parathyroids. In pregnancy, the teeth suffer particularly because of disturbances of the endocrines. The saying, "A tooth for every child," is said to have its equivalent in every language.
The influence of the prostate upon man's mental condition, and its contribution to the sex index, still remains to be investigated in detail. At the periods of interstitial cell hyperactivity, when a wave of radicalism in the blood sweeps through the tissues, the other endocrines are tested, and their latent stability or instability is made manifest.
The Anglo-Saxon tends to be more sharply pituitarized, his features are more clean-cut, his mentality more stable. The Frenchman is rather a cross between the Anglo-Saxon pituitary-centered and the Italian or Spanish adrenal-centered. So national resemblances, traceable to climatic influences being repeated from generation to generation upon the endocrines, may be explained physiologically.
We seem to be much nearer to grasping the nature of the unconscious, when we look upon it as a historical continuum, a compound or emulsion of different and various states of intravisceral pressure and tone, in the vegetative apparatus, dependent upon the balance between the endocrines, as well as upon past experiences of the viscera in the way of stimulation or depression.
If the thymus retrogresses after the second year, what takes its place as a brake upon the forward driving impulses of the other endocrines? We have every reason for assigning that rôle to the pineal. It performs its service mainly, in all probability, by inhibiting the sex stimulating effect of light playing upon the skin.
Feeding and environment indirectly, the state of the internal secretions as a whole directly, determine this. In girls, those definite signs, menstruation and the growth of the breasts, before the age of ten, mean premature awakening of the ovaries and a concomitant co-reaction of the other endocrines, creating the ensemble of maturity.
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