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Updated: June 16, 2025
In more severe infections the exudate consists of pus mixed with fibrin, and, it may be, red blood corpuscles purulent or suppurative synovitis; the synovial membrane and the ligaments are softened, and the surface of the membrane presents granulations resembling those on an ulcer; foci of suppuration may develop in the peri-articular cellular tissue and result in abscesses.
The adjacent joint may exhibit symptoms which vary from those of a simple effusion to those of a purulent arthritis. The joint symptoms may count for little in the clinical picture, or, as in the case of the hip, may so predominate as to overshadow those of the bone lesion from which they originated.
The process of ulceration may be defined as the molecular or cellular death of tissue taking place on a free surface. It is essentially of the same nature as the process of suppuration, only that the purulent discharge, instead of collecting in a closed cavity and forming an abscess, at once escapes on the surface.
He will more evidently and rapidly lose flesh. The huskiness will be more frequent and troublesome, and the discharge from the nose will have greater consistence. It will be often and violently sneezed out, and will gradually become more or less purulent. It will stick about the nostrils and plug them up, and thus afford a considerable mechanical obstruction to the breathing.
When the ear becomes dry from a deficiency of it, the hearing becomes imperfect, as also when it is thin and purulent. This wax not unfrequently becomes hard and obstructs the tube, causing less or more deafness.
Once I was not undressed for twenty-one days and nights; superintending and giving instructions on six or eight confinement cases in every twenty-four hours; lecturing three hours every afternoon to the class of midwives; giving clinical lectures to them twice a week, for an hour in the morning; superintending the care of some twenty infants, who were epidemically attacked with purulent ophthalmia; and having, besides, the general supervision of the whole department.
Some writers describe, under the head of canker, a violent chronic otitis, attended by a purulent sanguinoid discharge. Others understand by canker a species of erysipelatous inflammation, that makes its appearance on the inside of the flap, and extends itself to the interior of the ear.
In man also the clinical features of the chronic variety of the disease are somewhat different from those of the acute form. Here, too, infection takes place through a broken cutaneous surface, and leads to a superficial lymphangitis with nodular thickening of the lymphatics (farcy buds). The neighbouring glands soon become swollen and indurated. The primary lesion meanwhile inflames, suppurates, and, after breaking down, leaves a large, irregular ulcer with thickened edges and a foul, purulent or bloody discharge. The glands break down in the same way, and lead to wide destruction of skin, and the resulting sinuses and ulcers are exceedingly intractable. Secondary deposits in the subcutaneous tissue, the muscles, and other parts, are not uncommon, and the nasal mucous membrane may become involved. The disease often runs a chronic course, extending to four or five months, or even longer. Recovery takes place in about 50
Hence, even in the case of a being not subject to karman, its connexion with various unholy bodies will cause imperfection and suffering. And even when such a being voluntarily enters into such bodies in order to rule them, connexion with imperfections is unavoidable; no less than to be immersed in blood and purulent matter, even if done voluntarily, will make a man unclean.
In that case, should the instituting of a purulent discharge, in a neighbouring part, act in the manner which we would presume it may—should it by keeping up a constant discharge, not merely alter the determination, but diminish the inordinate action of the vessels in the diseased part; and at the same time excite the absorbents to such increased action as may remove the added matter; there will exist strong ground for hope, that a happy, though slow restoration to health, may be obtained.
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