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This unsoundness is common in heavy horses, especially if worked on city streets. The inflammation affects the cartilages of the front feet, rarely those of the hindfeet. The hereditary tendency toward the development of side-bones is an important predisposing factor. It is not uncommon to meet with this unsoundness in young horses that have never been worked.
"The peculiar Fever of 1843, as well as ordinary Typhus, now prevail much more extensively among the destitute Irish, hitherto unprotected by law, than among any others and the effect of all other predisposing causes, in favouring their diffusion, is trifling in comparison with Destitution, and its inseparable concomitant, crowding in ill-ventilated rooms.
'This, declared Lord Durham, 'is regarded by all other teachers of religion in the country as having at once degraded them to a position of legal inferiority to the clergy of the Church of England; and it has been most warmly resented. In the opinion of many persons, this was the chief predisposing cause of the recent insurrection, and it is an abiding and unabated cause of discontent.
One secret of its efficacy is, it stops the flow of thought toward the seat of difficulty, and so tends directly to reduce inflammation. At the same time it has a very bracing, invigorating effect. In the present case, it went right to the cause of the disease, which was discovered to be a spirit of fear, throwing open the pores and predisposing the subject to the attack.
In some other cases of native lepers I came upon similar histories; and while I do not believe that every case, or indeed perhaps a majority of cases, involves such a previous career of vice, I should say that this is certainly a strongly predisposing cause.
June is everywhere the suicide month, and December is everywhere the month in which self-destruction is least frequent. Durkheim gives tabulated statistics for seven of the principal countries of Europe, which show conclusively that, in point of predisposing tendency to suicide, the four seasons stand in the following order: summer first, spring second, autumn third, and winter last.
There was a Sabbath lull in the air, which, in a settlement unused to Sabbath influences, looked ominous. Mr. Oakhurst's calm, handsome face betrayed small concern of these indications. Whether he was conscious of any predisposing cause, was another question. "I reckon they're after somebody," he reflected; "likely it's me."
The stagnant water, which infected the stores, the cellars, and the dungeons of the public prison, no doubt diffused miasms in the air, which, as a predisposing cause, may have accelerated the development of the yellow fever; but I believe that the inundation of the Rio de la Guayra was no more the primary cause, than the overflowings of the Guadalquivir, the Xenil, and the Gual-Medina, were at Seville, at Ecija, and at Malaga, the primary causes of the fatal epidemics of 1800 and 1804.
A fossil species that was obliged to change its food or habits of life, did not of necessity undergo the particular set of modifications exhibited; but, under some slight change of predisposing causes as of season or latitude might have undergone some other set of modifications: the determining circumstance being one which, in the human sense, we call fortuitous.
PREDISPOSING CAUSES. Any condition that may lessen the resistance of the body or enable the tubercle bacillus to survive the exposure outside the body favors the development of the disease and the infection of the healthy animals. Crowded, poorly ventilated, filthy stables lower the disease-resisting power of the animal, and favor the entrance of the germs into the body.
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