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They notoriously suffered much from the ravages of malaria, and such as survived the baleful effects of this disease, escaped with impaired constitutions. Now this susceptibility to intermittent fever, appears to me to have been transmitted to their descendants, and to act as the predisposing cause.

What strikes me is a parallel in the predisposing causes of each attack. Your unexpected and gallant hand-to-hand encounter, at such desperate odds, with an experienced swordsman, like that insane colonel of dragoons, your fatigue, and, finally, your composing yourself, as my other friend did, to sleep." "I wish," he resumed, "one could make out who the coquin was who examined your letters.

"It would be difficult to determine, to what part of the Campagna, the disease is at present confined; but I should certainly not advise you, to sleep within the bounds of contagion, for the predisposing effects of sleep I have already hinted at.

The predisposing causes are such factors as tend to render the body more susceptible to disease or favor the presence of the exciting cause. Hogs confined in well-drained yards and pastures that are free from filth, and fed in pens and on feeding floors that are clean, do not become hosts for large numbers of parasites.

And even in the modern world we must in most instances be content to fix a period, we may perhaps add a local habitation, within the limits of which the term must have been born, either in legitimate scientific travail, or the child of some flash of genius, or the product of some generatio aequivoca, the necessary result of exciting predisposing causes; at the same time seeking by further research ever to narrow more and more the limits within which this must have happened.

Some of the parasitic insects, mosquitoes, flies and ticks, act as secondary hosts for certain animal microorganisms that they transmit to healthy individuals through the punctures or the bites that they are capable of producing in the skin. CAUSES. For convenience we may divide the causes of disease into the predisposing or indirect, and the exciting or direct.

Syphilis plays an important part in the production of aneurysm, probably by predisposing the patient to arterio-sclerosis and atheroma, and inducing an increase in the vascular tension in the peripheral vessels, from loss of elasticity of the vessel wall and narrowing of the lumen as a result of syphilitic arteritis.

A chance quarrel between Aristagoras of Miletus and the Persian Megabates, pecuniary difficulties pressing on the former, and the natural desire of Histiseus, father-in-law of Aristagoras, to revisit his native place, were undoubtedly the direct and immediate causes of what became a great national outbreak. That there must have been other and wider predisposing causes can scarcely be doubted.

It may also be said that an indifference to sexual relationships, a tendency to attach no personal value to them, is often a predisposing cause in the adoption of a prostitute's career; the general mental shallowness of prostitutes may well be accompanied by shallowness of physical emotion.

Birds having a mild form of roup, or that have recently recovered from it, are common carriers of the disease. The disease is usually introduced into the flock by allowing birds exposed at poultry shows, or recently purchased breeding stock from an infected flock, to mix with the healthy birds. The predisposing causes are very important factors in the development of roup.