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Updated: May 16, 2025
Imperfect circulation is an important causative factor in ulceration, especially when it is the venous return that is defective. This is best illustrated in the so-called leg ulcer, which occurs most frequently on the front and medial aspect of the lower third of the leg.
The differences in inflammation in the two cases is really one of degree, and the classification is made to coincide with this probable fact. it is, of course, clinically recognized that endocarditis following certain diseases, especially rheumatism, is of the simple or mild type, while that termed ulcerative endocarditis may occur apparently as a primary or general infection, and the causative bacteria, as a rule, are readily discovered in the blood.
Henceforth, I will not trouble you, but abjure the subject; except, indeed, my sturdy friend "the Squire," soon to be introduced to you, insists upon his after-dinner topic: but we will cut him short; for, in fact, nothing can be more provoking, tedious, useless, and causative of ill-blood, than this perpetual intermeddling of private ignoramuses, like him and me, with matters they do not understand, nor can possibly ameliorate.
Differences in race, religion and age are recognized as having a causative relation to desertion. Miss Brandt found that, in about 28 per cent of the cases where these facts were ascertained, the husband and wife were of different nationality.
It is noteworthy that in most cases of uncomplicated stuff-fetichism the attraction apparently arises on a congenital basis, as it appears in persons of nervous or sensitive temperament at an early age and without being attached to any definite causative incident. The sexual excitation is nearly always produced by the touch rather than by the sight.
It is at least fifty or sixty miles long and runs along the base of the Apennines in a line almost perfectly straight. Does not its parallelism with the mountain chain suggest a causative relation? See that other mighty rill, at least a hundred and fifty miles long, starting directly north of it and pursuing so true a course that it cleaves Archimedes almost cleanly into two.
What man, unless completely depraved by vice or weighed down by care and cupidity, has not experienced once, at least, before his death, the attraction of solitude?" While the motives just described were unquestionably preeminent among the causative factors in monasticism, it should not be taken for granted that there were no others, or that either or both of these motives controlled every monk.
Initial attempts to find a causative agent had all three of the Lancet's crew spending sleepless nights for a week, but Jack's careful study of the pattern of the disease and the biochemical reactions that accompanied it brought out the answer: the disease was caused by a rare form of genetic change which made crippling alterations in an essential enzyme system.
Other causes might be assigned, causative of nautical superstition, and tending to feed it. But enough. It is well known that the whole family of sailors is superstitious.
Naturally, these should be clean to the sight, but it is in invisible dirt that serious danger lurks; bacteria are the causative agents of this disease. Experiments have taught the bacteriologist that disease-producing organisms are killed in half an hour when subjected to a high atmospheric pressure and the temperature of steam.
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