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Updated: June 26, 2025


Magendie also divided his typhoid fever patients into two classes, to one of whom he prescribed the ordinary remedies, and to the other no medicines at all, relying wholly on such nursing and such attention to Hygiene as the vital instincts demanded and common sense suggested. Of the patients who were treated the usual way, he lost the usual proportion, about one-fourth.

The dance drew to an end, and I approached my hostess, pointed the girl out, and asked for an introduction. Her name was Margot Magendie, I found, and she was an heiress as well as a beauty. I did not care. It was her humanity that drew me, nothing else.

The use of prussic acid in the cure of consumptions, lately suggested by M. Magendie, at Paris, is little more than the revival of the Dutch practice in this disorder; for Linnaeus informs us, that distilled laurel water was frequently used in the cure of pulmonary consumption.

Vichy was more efficacious than Carlsbad water. Hot water was found to have an effect on the bile much like that of the mineral waters. Although Magendie is rightly considered the true initiator of experimentation upon living beings, the practice of vivisection is as old as science itself. Five centuries before him, under the Ptolemies, Egyptian experimenters had operated upon condemned persons.

Coupled with the new method of physical diagnosis in the effort to substitute knowledge for guess-work came the studies of the experimental physiologists in particular, Marshall Hall in England and Francois Magendie in France; and the joint efforts of these various workers led presently to the abandonment of those severe and often irrational depletive methods blood-letting and the like that had previously dominated medical practice.

What procureur has ever ventured to draw up an accusation against M. Magendie or M. Flourens, in consequence of the rabbits, cats, and guinea-pigs they have killed? not one. So, then, the rabbit dies, and justice takes no notice.

But; strange to say, when the moment for the introduction arrived, and I stood face to face with Miss Magendie, I felt an extraordinary shrinking from her. I have never been able to understand it, but my blood ran cold, and my pulses almost ceased to beat. I would have avoided her; an instinct within me seemed suddenly to cry out against her.

For even if we could try experiments upon a nation or upon the human race, with as little scruple as M. Magendie tried them on dogs and rabbits, we should never succeed in making two instances identical in every respect except the presence or absence of some one definite circumstance.

In another way, too, medicine was greatly helped by the rise of experimental pathology, which had been introduced by John Hunter, was carried along by Magendie and others, and reached its culmination in the epoch-making researches of Claude Bernard.

There is a terrible parallax between the period before thirty and that after threescore and ten, as two men of those ages look, one with naked eyes, one through his spectacles, at the man of fifty and thereabout. Magendie, I doubt not you have all heard of. I attended but one of his lectures.

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