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Updated: May 14, 2025
The induration results from coagulation and partial organisation of the inflammatory effusion, and prevents the necessary contraction of the sore. The base of a callous ulcer lies at some distance below the level of the swollen, thickened, and white edges, and presents a glazed appearance, such granulations as are present being unhealthy and irregular.
Scleroderma neonatorum is an induration of the skin, congenital and occurring soon after birth, and is invariably fatal. A disease somewhat analogous is edema neonatorum, which is a subcutaneous edema with induration affecting the new-born. If complete it is invariably fatal, but in a few cases in which the process has been incomplete recovery has occurred.
Interference with the nutrition of a part by œdema or chronic venous congestion may impede healing; as may also induration of the surrounding area, by preventing the contraction which is such an important factor in repair. Defective innervation, such as occurs in injuries and diseases of the spinal cord, also plays an important part in delaying repair.
"A black character, a womanish character, a stubborn character: bestial, childish, stupid, scurrilous, tyrannical." A pagan, who had observed such a character in its working, prayed to be preserved from it. Christians of the twentieth century must not sink below the moral level of Marcus Aurelius. My discourse on "Induration" was intended to convey a warning which, as individuals, we all need.
In relation to the meatus and canal of the urethra, in either of which situations the swelling and induration may lead to narrowing of the urethra, so that the urine is passed with pain and difficulty and in a minute stream; stricture results only in the exceptional cases in which the chancre has ulcerated and caused destruction of tissue.
As I put my hand on his shoulders in a familiar way, to make myself at home with him, and to remove the timidity with which my sudden appearance seemed to inspire him, by a pleasant word or two of greeting, his flesh felt case-hardened into all the induration of toiling manhood, and as unsusceptible of growth as the anvil block.
This induration seems to have been occasioned by the constant afflux of the nutritive juices, which were stopt at that place, and deprived of their most liquid parts; the grosser ones being unable to spread in the boney cavity, by which they were confined, could only acquire a greater solidity, and change a soft body into a hard and nearly osseous mass.
Each was initiated into that degree to which the induration of his conscience and the character of his discontent made him eligible, and in which he could be most serviceable, the body of the people still cheating themselves with the false sense of security begotten of the belief that they were somehow exempt from the operation of all agencies inimical to their national welfare and integrity.
The pointer, somewhat too heavy before, and hardly worked, becomes what is called chest-foundered. From his very make it is evident that, in long-continued and considerable exertion, the subscapular muscles will be liable to sprain and inflammation. There will be inflammation of the fasciae, induration, loss of power, loss of nervous influence and palsy.
And as for you, my dear brethren and countrymen of Scotland, as it is long since first Christianity was preached and professed in this land, as also it was blessed with a most glorious and much-renowned Reformation: and, further, as the gospel hath been longer continued in purity and peace with us than with any church in Europe: moreover, as the Church of Scotland hath treacherously broken her bonds of oath and subscription wherewith other churches about us were not so tied; and, finally, as Almighty God, though he hath almost consumed other churches by his dreadful judgments, yet hath showed far greater long-suffering kindness towards us, to reclaim us to repentance, though, notwithstanding all this, we go on in a most doleful security, induration, blindness, and backsliding: so now, in the most ordinary course of God’s justice, we are certainly to expect, that after so many mercies, so great long-suffering, and such a long day of grace, all despised, he is to send upon us such judgments as should not be believed though they were told.
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