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Updated: May 14, 2025
Scleroderma neonatorum is an induration of the skin, congenital and occurring soon after birth, and is invariably fatal. A disease somewhat analogous is edema neonatorum, which is a subcutaneous edema with induration affecting the new-born. If complete it is invariably fatal, but in a few cases in which the process has been incomplete recovery has occurred.
The atrophic type of scleroderma is preceded by an edema, and from pressure-atrophy of the fat and muscles the skin of the face is strained over the bones; the lips are shortened, the gums shrink from the teeth and lead to caries, and the nostrils are compressed. The etiology and pathology of this disease are quite obscure.
"Genus Balistes, family Scleroderma, order Plectognatha," Conseil muttered. Assuredly, Ned and Conseil in combination added up to one outstanding naturalist. The Canadian was not mistaken. Cavorting around the Nautilus was a school of triggerfish with flat bodies, grainy skins, armed with stings on their dorsal fins, and with four prickly rows of quills quivering on both sides of their tails.
Such epidermic anomalies as ichthyosis, scleroderma, and molluscum simplex, sometimes appearing shortly after birth, but generally seen later in life, will be spoken of in the chapter on Anomalous Skin Diseases. Human horns are anomalous outgrowths from the skin and are far more frequent than ordinarily supposed. Nearly all the older writers cite examples.
Happily the prognosis is good, as there is a tendency to spontaneous recovery, although the convalescence may be extended. Although regarded by many as a disease distinct from scleroderma, morphea is best described as a circumscribed scleroderma, and presents itself in two clinical aspects: patches and bands, the patches being the more common.
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