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Luther's contemporaries at once recognized the great importance of the treatise, for within the period of seven months it passed through eight editions; these were followed by six more editions between the years of 1521 and 1525; in 1521 it was translation into Latin, and in this form passed through three editions up to the year 1525; and all this in spite of the fact that in those years the so-called three great Reformation writings of 1520 were casting all else into the shadow.

Van der Hulst, a person of infamous character, was not the man to render the institution less odious than it was by its nature. Before he had fulfilled his duties two years, however, he was degraded from his office by the Emperor for having forged a document. In 1525, Buedens, Houseau and Coppin were confirmed by Clement the Seventh as inquisitors in the room of Van der Hulst.

To this formidable enemy Francis opposed his weak and presumptuous favorite, the Admiral Bonnivet, who was driven out of Italy in 1524, the year in which the gallant Bayard lost his life in striving to redeem his commander's errors. The confidence of Francis seemed to increase with his dangers, and his faults with his confidence. He again entered the Milanese in 1525, and retook the capital.

Francis made no objection to this design. On the 12th of May, 1525, he wrote to his mother, "Madame, the bearer has assured me that he will bring you this letter safely; and, as I have but little time, I will tell you nothing more than I shall be off to Naples on Monday , and so keep a lookout at sea, for we shall have only fourteen galleys to take us and eighteen hundred Spaniards to man them; but those will be all their arquebusiers.

The great work of Las Casas, however, still remains inedited, "A General History of the Indies from 1492 to 1525." Like his other works, it shows marks of haste and carelessness, but its value is great, notwithstanding his too fervent zeal for the Indians.

Thomas Münzer, the only leader of the movement of 1525 who seems to have been acquainted with the Zürich enthusiasts, was by no means at one with them on many points, notably refusing to attach any importance to their special sign, rebaptism. Chief among the Zürich coterie may be mentioned Konrad Grebel, at whose house the sect first of all assembled.

During the first two years five Latin editions were printed, and up to 1525 seven German editions. A translation was published in the Netherlands in 1521, and one in England in 1578.

As in 1525, they were promptly crushed by the German princes, Catholic and Protestant, of the neighborhood; but their rising had created some reverberation in France, and the Reformers had been suspected of an inclination to take part in it.

Two to the same effect from Amilcare Anguissola in Cremona acknowledge services rendered to his daughter Sofonisba, who was studying design in Rome. Pietro Urbano wrote twenty letters between the years 1517 and 1525, addressing him in terms like "carissimo quanto padre."

In the few months that intervened before his death he made the power of Portugal once more respected in the East. When he died in Cochin, in 1525, he was mourned by the natives as a just ruler, and by his countrymen as one who had saved to Portugal the richest part of the national domain.