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Updated: May 7, 2025
Through contemporary observations, as well as through later investigations, it is easy to ascertain that all more intensive affective processes, even excitements of a terrifying nature, encroach upon sexuality; this can at all events furnish us with a contribution to the understanding of the pathogenic action of such emotions.
These, of course, constitute the pathogenic species, or so called "disease germs". Only such species as can overcome this first resistance can be disease germs, for they alone can retain their foothold in the body. But how do these species overcome the poisons, which kill the other harmless bacteria?
All this shows that there are other factors in determining the course of a disease, or even the existence of a disease, than the simple presence of a peculiar species of pathogenic bacterium. From the facts just stated it will be evident that any list of germ diseases will be rather uncertain.
Then he found cases in which, besides bacteria of one definite and constant form, there were others also accumulated within and around the tubular glands, of various size, some short and thick, others very fine; and be soon concluded that he had to do here with a primary invasion of pathogenic bacilli, which, as it were, prepared the tissues for the entrance of the non-pathogenic forms, just as he had observed, in the necrotic, diphtheritic changes in the intestinal mucosa and in typhoid ulcers.
But the essential evils of each system are essential evils, and one has to suffer them and struggle against them, as one has to struggle perpetually with the pathogenic bacteria that infest the world. The theory of monarchy is, no doubt, inferior to the democratic theory in stimulus, but the latter fails in qualitative effect, much more than the former.
A specific polyarthritis or synovitis which attends navel infection of foals is perhaps the most frequent form of arthritis that is to be considered metastatic. This condition is truly a disease of young animals and, while it is a specific arthritis, the cause is yet to be attributed to any definite pathogenic organism with certainty.
On the other hand, other conditions will cause an increase in the virulence of a pathogenic germ. The virus which produces hydrophobia is increased in violence if it is inoculated into a rabbit and subsequently taken from the rabbit for further inoculation.
Above all, it is telling us what becomes of the pathogenic bacteria after being eliminated from the body of the patient; how they may exist for a long time still active; how they may lurk in filth or water dormant but alive, or how they may even multiply there.
If a pathogenic bacterium succeeds in passing the outer safeguards and entering the body, and if it then succeeds in overcoming the forces of resistance which we have already noticed, it will begin to multiply and produce mischief. This multiplication now goes on for a time unchecked, and there is little reason to expect that we can ever do much toward checking it by means of drugs.
And thus gradually had I become permeated with the recognition of a region hitherto unknown to me, and that I had always depreciated in others and especially, it now occurred to me, in my friend the old folk-lorist. Here surely, I thought, was the beginning of conditions which, carried a little further, must become pathogenic. That the change was real and pregnant I had no doubt whatever.
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