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Updated: May 7, 2025


Not only do they produce different kinds of poisons giving rise to different symptoms of poisoning; not only do they produce different results in different animals; not only do the different pathogenic species differ much in their power to develop serious disease, but the different species are very particular as to what species of animal they attack.

Synovia is a good culture medium and the environment is ideal for multiplication of bacteria; consequently, the grave disturbances which may attend the introduction of pathogenic organisms into a synovial cavity as the result of a puncture wound are not to be forgotten.

Even vaccination, as is well known, sometimes, through faulty methods, results fatally, and it is a very serious thing to experiment upon human beings with anything so powerful for ill as pathogenic bacteria.

If the bacteria develop continuously, the fever is constant instead of intermittent, since the adequate stimulus is constantly present. Bacteriology has taught us that both heat and cold are fatal to pathogenic infections; for this reason either of the apparently contradictory methods of treatment may help, i. e., either hot or cold applications.

They thus act as scavengers These corpuscles certainly have some agency in warding off the attacks of pathogenic bacteria Very commonly they collect in great numbers in the region of the body where invading bacteria are found.

Digestion first becomes difficult, the cutaneous inflammation excites profuse perspirations, an unquenchable thirst succeeds, and, in persons of a feeble constitution, increasing impatience is succeeded by depression of mind, during which all the pathogenic causes act with increased violence.

Pathogenic bacteria are so widely distributed, that in the ordinary circumstances of everyday life, no matter how trivial a wound may be, or how short a time it may remain exposed, the access of organisms to it is almost certain unless preventive measures are employed.

It has not by any means been shown that all pathogenic germs produce their effect in this way, but it has been proved to be the real method in quite a number of cases, and is extremely probable in others. While some bacteria perhaps produce results by a different method, we must recognise the production of poisons as at all events the common direct cause of the symptoms of disease.

It is this factor, doubtless, which in a large measure determines the severity of any epidemic of a bacterial contagious disease. The very great modification of our early views has affected our ideas as to the power which individuals have of resisting the invasion of pathogenic bacteria.

The fact will some day be generally recognized, as it is today by a few, that the so-called pathogenic bacteria or germs have no power to injure a healthy body, that there is bodily degeneration first and then the system becomes a favorable culture medium for germs: In other words, disease comes first and the pathogenic bacteria multiply afterwards.

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