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Fatty degeneration may occur in the papillary growths with necrotic changes, and this may lead to the formation of atheromatous ulcers which may later become covered with lime deposits, and then a hard calcareous ring may form.
Infection occasions more pronounced local symptoms of inflammation and, because of the rapid progress of necrotic destruction of cartilage, the course of the affection is usually rapid; ankylosis is a frequent result and loss of the subject is often inevitable. However, in non-infective arthritis of the fetlock joint, prognosis is favorable. Treatment.
The frog skin was transferred to the left buttocks, and on the right buttocks eight long strips of white skin were transferred after the manner of Thiersch. A strip of human skin was placed in one section over the frog skin, but became necrotic in four days, not being attached to the granulating surface. The man was discharged cured in six months.
The organism does not readily establish itself in the human body, and seems to flourish best when it finds a nidus in necrotic tissue and is accompanied by aërobic organisms, which, by using up the oxygen in the tissues, provide for it a suitable environment. The presence of a foreign body in the wound seems to favour its action.
Then he found cases in which, besides bacteria of one definite and constant form, there were others also accumulated within and around the tubular glands, of various size, some short and thick, others very fine; and be soon concluded that he had to do here with a primary invasion of pathogenic bacilli, which, as it were, prepared the tissues for the entrance of the non-pathogenic forms, just as he had observed, in the necrotic, diphtheritic changes in the intestinal mucosa and in typhoid ulcers.
Such cases are found in old light-harness or saddle-horses that have been more or less lame for years and where there exists marked contraction of the heels, rough hoof walls, and hard and atrophied frogs. Suppurating corns require surgical attention in the way of removal of the purulent necrotic mass and making provision for drainage.
This is most efficiently accomplished by the knife or scissors, cutting until the tissue bleeds freely, after which the raw surface is painted with undiluted carbolic acid and dressed with iodoform gauze. It may be necessary to remove large pieces of bone when the necrotic process has implicated the jaws.
Probably the most remarkable feature of this curious accident was the fact that there was no fracture or injury to the bone, and it was thought possible that the function of the arm would be but little impaired. Tousey reports a case of foreign body in the axilla that was taken for a necrotic fragment of the clavicle.
"The clinical history is in every respect typical and instructive. "It shows us that the origin of peritonitis which is by far the most common, is in a diseased appendix. At the autopsy this was found necrotic and perforated.
A variable degree of lameness is manifested in different cases. Treatment. Two general plans of handling this disease are in vogue. One, the more popular method, consists in the injection of caustic solutions of various kinds into the fistulous openings with the object of causing sloughing of necrotic tissue and the stimulation of healthy granulation of such wounds.
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