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Updated: May 9, 2025
"He hath been spoken to in the language of a Christian, no less than in that of a heathen, and as yet no reply hath been made, while he obeys commands uttered in both forms of speech." "It mattereth not," said Ergot, dismounting and drawing near to his subject, with a look towards Dudley that should seem to court his admiration.
Perhaps there is no class of cardiac diseases in which more frequent striking relief can be obtained than in these cases of mitral stenosis. If the congestion of the lungs is very great, and death seems imminent from cardiac paralysis, if cyanosis is serious, and bloody. frothy mucus is being expectorated, venesection and an intramuscular injection of aseptic ergot may be indicated.
When venesection is not indicated in certain conditions of low blood pressure and heart failure, ergot has saved life. It causes contraction of the blood vessels and seems to tone the heart. Incidentally it quiets the central nervous system. If the blood pressure is much increased by it, the ergot should not be repeated, as too much work should not be thrown on the heart muscle.
A, Metacarpal bone; B, first phalanx; C, second phalanx, D, third phalanx; E, distal sesamoid bone; 1, volar pouch of capsule of fetlock joint; 2, inter-sesamoidean ligament; 3, 4, proximal end of digital synovial sheath; 5, ring formed by superficial flexor tendon; 6, fibrous tissue underlying ergot; 7, ergot; 8, 9, 9', branches of digital vessels; 10, distal ligament of distal sesamoid bone; 11, suspensory ligament of distal sesamoid bone; 12, 12', proximal and distal ends of bursa podotrochlearis.
Such stimulation, however, Pilcher and Sollmann believe may be secondary to asphyxia. Nicotin they found to cause intense stimulation of the vasomotor center. Ergot and hydrastis and its alkaloids seem to have no effect on the vasomotor center. Strophanthus acted on this center only moderately, and digitalis very slightly, if at all.
The effects and symptoms arising from the continued use of the ergot of rye, as manifested in the human system, have been but briefly hinted at by authors, and, probably, some of them are only reasonable conjectures. All they say is, that it produces violent headache, spaculation in the extremities, and death.
Cardiac Tonics: Digiralis, strophanthus, caffein, strychnin. 2. Cardiac Stimulants: Camphor, alcohol, ammonia. 3. Vasodilators: Nitrites, iodids, thyroid extract. 4. Cardiac Nutritives: Iron, calcium. 5. Cardiac Emergency Drugs: Ergot, suprarenal active principle, pituitary active principle, atropin, morphin, and also some of the drugs already mentioned.
For a bitch of 10 lb. in weight ten drops of the extract of ergot in a teaspoonful of water should be ample, given by the mouth. The scissors are for severing the umbilical cord if the mother should fail to do it in her own natural way. Sometimes a puppy may be enclosed within a membrane which the dam cannot readily open with tongue and teeth.
If after a certain time some, although little, progress has been made, the ergot must be continued in smaller doses, or perhaps suspended for a while; but, if all progress is evidently suspended, recourse must be had to the hook or the forceps. By gentle but continued manipulation much may be done, especially when the muzzle of the puppy can be brought into the passage.
The necessity for this must have been forcibly impressed upon the minds of the inhabitants of our country from the experience of the last ten or twelve years. Mr. Pierce is convinced that these symptoms are produced by the continued use of the ergot, or spur of the June grass, the effects being similar to those produced upon the human family by long-continued use of ergot of rye.
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