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Updated: May 1, 2025
This organism has been found in pure culture in suppurative conditions of bone, of cellular tissue, and of internal organs, especially during convalescence from typhoid fever. Like the staphylococcus, it is capable of lying latent in the tissues for long periods. Other Pyogenic Bacteria.
The most common is an osteomyelitis commencing in the marrow exposed in a wound infected with pyogenic organisms. In amputation stumps, fungating granulations protrude from the sawn end of the bone, and if necrosis takes place, the sequestrum is annular, affecting the cross-section of the bone at the saw-line; or tubular, extending up the shaft, and tapering off above.
Indeed, such a procedure would be objectionable, as it would stimulate the pyogenic membrane to unnecessary suppuration. All that is requisite is to guard against the introduction of living atmospheric germs from without, at the same time that free opportunity is afforded for the escape of the discharge from within.
The mother died, and there was no autopsy. On May twenty-eighth, a rabbit was inoculated under the skin of the abdomen with five drops of the preceding culture of the pyogenic vibrio. The days following an enormous abscess formed which opened spontaneously on the fourth of June. An abundantly cheesy pus came from it. About the abscess there was extensive induration.
This is liable to be mistaken for rheumatic fever, from which, however, it differs in that there is no real migration from joint to joint; there is an absence of sweating and of cardiac complications; and no benefit follows the administration of salicylates. In exceptional cases, tuberculous joint disease follows an acute course resembling that of the pyogenic arthritis of infants.
#Formation of an Abscess.# When pyogenic bacteria are introduced into the tissue there ensues an inflammatory reaction, which is characterised by dilatation of the blood vessels, exudation of large numbers of leucocytes, and proliferation of connective-tissue cells.
#Teno-synovitis.# The toxic or infective agent is conveyed to the tendon sheaths through the blood-stream, as in the gouty, gonorrhœal, and tuberculous varieties, or is introduced directly through a wound, as in the common pyogenic form of teno-synovitis. Teno-synovitis Crepitans.
Burns of Second Degree Vesication of the Skin. These are characterised by the occurrence of vesicles or blisters which are scattered over the hyperæmic area, and contain a clear yellowish or brownish fluid. On removing the raised epidermis, the congested and highly sensitive papillæ of the skin are exposed. Unna has found that pyogenic bacteria are invariably present in these blisters.
From the point of view of the surgeon the most important varieties of micro-organisms are those that cause inflammation and suppuration the pyogenic bacteria. This group includes a great many species, and these are so widely distributed that they are to be met with under all conditions of everyday life.
The differential diagnosis from other forms of pyogenic infection is established by bacteriological examination of the fluid withdrawn from the joint. The treatment is carried out on the same lines as in other pyogenic infections, considerable reliance being placed on the use of autogenous vaccines.
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