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Updated: May 5, 2025
He walked over and pulled down a well-thumbed standard work on toxicology, turned the pages, then began to read aloud: Pure aconitin is probably the most actively poisonous substance with which we are acquainted and, if administered hypodermically, the alkaloid is even more powerfully poisonous than when taken by the mouth.
Stomach-tube and free lavage; cold affusion; drawing forward tongue; artificial respiration; galvanism and suspension with head downward. Inhalation of nitrite of amyl; strychnine hypodermically. Fatal Dose. When swallowed, from 1 to 2 ounces. Method of Extraction from the Stomach.
Morphine may be given hypodermically to the large animals after a period of six to eight hours following the administration of the physic. The following formula is quite useful in checking diarrhoea: salol one-half ounce, bismuth subnitrate one ounce, and bicarbonate of soda two ounces.
The patient, who is a very intelligent man, said he had felt worse during the day, and in the evening, his knee, which had been somewhat painful for two or three days, had become exceedingly painful. I gave morphine, hypodermically, and went home, leaving some morphine for the night. The next day I saw him. The pain had been relieved by the morphine, still occasionally it was quite severe.
It is rotting the heart out of the Tenderloin. Did you notice Veronica Haversham's yellowish whiteness, her down-drawn mouth, elevated eyebrows, and contracted eyes? She may have taken it up to escape other drugs. Some people have and have just got a new habit. It can be taken hypodermically, or in a tablet, or by powdering the tablet to a white crystalline powder and snuffing up the nose.
While a large dose of strychnin, even to one-twentieth grain hypodermically, may be used once in serious emergency when it is deemed the drug to use, a dose larger than one-thirtieth grain hypodermically is rarely indicated, the frequency of such a dose should seldom be more than once in six hours, and a smaller close of strychnin may act more satisfactorily.
The first indication is met by the administration of emetics, to produce vomiting, or by the application of the stomach-tube. The best emetic is that which is at hand. If there is a choice, give apomorphine hypodermically. The dose for an adult is 10 minims. It may be given in the form of the injection of the Pharmacopoeia, or preferably as a tablet dissolved in water.
A few much larger doses may be given if desired. A cup of coffee may be given the patient medicinally: as a substitute for the drug, an ordinary cup of strong coffee containing between 2 and 3 grains. Other preparations of caffein may be selected if desired, or a soluble preparation may be given hypodermically.
Strychnin should be avoided, if possible, in the evening in order that the patient may sleep. Whether it should be given by the mouth or hypodermically would depend entirely on the seriousness of the condition. Once in six hours is generally often enough for strychnin to be administered unless the dose is very small. It is rarely, if ever, advisable to use alcohol.
A treatment as successful as any in this heart weakness in delirium tremens is morphin sulphate, 1/2 grain, and atropin, 1/15 grain, given hypodermically, with the administration of digitalis hypodermically for its later action on the heart. If the heart is contracting very rapidly, an ice-bag over the precordia will often quiet it.
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