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According to Lewin, Brochin reported a case in which the idiosyncrasy to morphin was so great that 1/25 of a grain of the drug administered hypodermically caused irregularity of the respiration, suspension of the heart-beat, and profound narcosis.
When it was raised to 140"HGs under the influence of pituitrin there was marked depression as is shown in the chart for July, 1912. Pituitrin given in m. v. hypodermically three times a day, and after some days in larger doses by the mouth, kept the pressure between 125" HGs and 130" HGs, but with no corresponding mental improvement.
She had become very slow in speech and gait, sensitive to cold, and languid and depressed in spirit to the point of inability to go about alone. Murray, employing the glycerin extract of the thyroid gland of a freshly killed sheep, injected twenty-four drops hypodermically, twice a week.
A few drops of an epinephrin solution 1:1,000 may be placed on the tongue, and repeated three times a day, or from 5 to 10 minims of a weaker solution may be given hypodermically. The usual precautions against overeating, overdrinking, severe physical exercise, sudden movements, overuse of tobacco, etc., should all be urged on the patient.
The patient may recover if allowed to remain in a recumbent position, but stimulants by mouth e.g., ammonia and the hypodermic injection of brandy or ether may be necessary, with the inhalation of nitrite of amyl. The =Cocaine Habit= consists in the self-administration of the drug hypodermically. It induces excitement, which is followed by prostration.
Give chloride of ammonium in 30 grain doses to prevent delirium; strychnine or digitalin hypodermically. Method of Extraction from the Stomach. Neutralize the contents of the stomach, if acid, with sodium carbonate; place them in a retort and carefully distil. Collect the distillate, mix with chloride of calcium or anhydrous sulphate of copper, and again distil.
He gives it hypodermically, 15 minims at the first dose and 5 minims subsequently, until the systolic pressure is reduced to 140 or less. He admits that this is rather strenuous treatment. He does not speak of treatment by thyroid extracts, which has been regarded as valuable by some other workers. In these patients who show eclamptic symptoms, he maintains a milk diet, and purging and sweating.
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