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Updated: June 21, 2025
We now call these toes "vestigial," and know the pig's ancestors used them, walking on four toes and not on two, as at present. Buffon believed there were degenerations as well as developments, and considered the ape a degenerate man. He conceived these changes to be brought about by what he called the favors and disfavors of nature.
Endocrine types have other tendencies, which when studied and controlled, will decimate the great assassins of middle age: heart disease and kidney disease, with accompanying degenerations of the blood vessels and circulation. The adrenocentric tends to get up a hyperacidity of the stomach and a high blood pressure, besides certain forms of diseases of the lungs.
Changes in stomach and liver, in kidneys and lungs, in the blood-vessels to the minutest capillary, and in the blood to the smallest red and white blood disc disturbances of secretion, fibroid and fatty degenerations in almost every organ, impairment of muscular power, impressions so profound on both nervous systems as to be often toxic these, and such as these, are the oft manifested results.
These are not the degenerations of age, but the blood-supplying, blood-making, and blood-elaborating organs of the body have completed the growth of the organism, done their work, and are striking a balance with the needs of the economy.
If generous honesty, valor, and plain dealing be the cognizance of thy family or characteristic of thy country, hold fast such inclinations sucked in with thy first breath, and which lay in the cradle with thee. Fall not into transforming degenerations, which under the old name create a new nation.
Such irregularity perhaps most frequently occurs with valvular disease, especially mitral stenosis and in the muscular degenerations of senility, as fibrosis. Atropin has been used to differentiate functional heart block from that produced by a lesion. Jour. Med. In the first the heart block is induced by digitalis. This was entirely removed by atropin.
In the pent-in evils which pathology so often shows occurrent in the case of spirit-drinkers, in the vascular, fatty and fibroid degenerations which take place, in the accumulations of rheumatic and scrofulous tendencies, there is the strongest evidence that "and is very prone to initiate serious disturbances amid the normal conduct both of organ and function.
Statistics prove that there are more deaths between the ages of 40 and 50 from cardiovascular-renal disease, that is from heart, arterial and kidney degenerations, than formerly.
What certain Kinds of Commotion or Dislocation of the Parts of a Body may do towards the Changing its Colour, is not only evident in the Mutations of Colour observable in Quick-silver, and some other Concretes long kept by Chymists in a Convenient Heat, though in close Vessels, but in the Obvious Degenerations of Colour, which every Body may take notice of in Bruis'd Cherries, and other Fruit, by comparing after a while the Colour of the Injur'd with that of the Sound part of the same Fruit.
True angina pectoris probably does not occur without some serious organic disease of the heart, mostly coronary sclerosis, fatty degeneration of the heart muscle, adherent pericarditis and perhaps some nerve degenerations.
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