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Updated: May 14, 2025
"Infantry, and all the other branches, in a healthy body and our own body is healthy. Watch our phagocytes come forward now, just as those tiny white corpuscles rush through the blood to an invaded spot. You'll see 'em come quick. Herman, your country has licked Belgium and Serbia you can rightly claim that much. But she'll never get another decision. Too many phagocytes."
Within the area thus circumscribed the struggle between the bacteria and the phagocytes takes place, and in the process toxins are formed by the organisms, a certain number of the leucocytes succumb, and, becoming degenerated, set free certain proteolytic enzymes or ferments.
It attaches itself to them: that is the essential fact. In many of us the phagocytes are not at a given moment so "avid" of this or that disease-microbe as they should be in order to protect us from its multiplication and poison production. The dead microbes answer this purpose; they excite the production of the opsonin appropriate to them and yet are not themselves dangerous, since they are dead.
These resistant forces are in part associated with the productions of body poisons, and are in part associated with the active powers of special cells which have been called phagocytes. The origin of the poisons and the exact method of action of the phagocytes we may well leave to the future to explain. These resisting powers of the body will vary with conditions.
In four and twenty hours Hampton had "caught" Syndicalism. All day Tuesday, before the true nature of the affection was developed, prominent citizens were outraged and appalled by the supineness of their municipal phagocytes.
Once she turned the sub-stage mirror a bit to catch the light streaming in the window. Brion stood behind her, fists clenched, forceably controlling his anxiety. "What do you see?" he finally blurted out. "Phagocytes, platelets ... leucocytes ... everything seems normal." Her voice was dull, exhausted, her eyes blinking with fatigue as she stared into the tube.
The dead bone is separated from the living by the agency of granulation tissue with its usual complements of phagocytes and osteoclasts, so that the sequestrum presents along its margins and on its deep surface a pitted, grooved, and worm-eaten appearance, except on the periosteal aspect, which is unaltered.
In all cases, however, the process is a natural one and dependent upon the vital activity of the body. It is based at the foundation, doubtless, upon the powers of the body cells, either the phagocytes or other active cells. The body has, in short, its own forces for repelling invasions, and upon these forces must we depend for the power to produce recovery.
They multiply too rapidly, and sometimes they produce secretions which actually drive the phagocytes away. Commonly, as already noticed, the corpuscles are attracted to the point of invasion, but in some cases, when a particularly deadly and vigorous species of bacteria invades the body, the secretions produced by them are so powerful as actually to drive the corpuscles away.
There has been not a little dispute, however, as to the method by which they carry on the conflict. This idea gave rise to the theory of phagocytosis, and the corpuscles were consequently named phagocytes. The study of several years has, however, made it probable that this is not the ordinary method by which the corpuscles destroy the bacteria.
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