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Updated: May 12, 2025
Salvarsan has not been proved of value. Intestinal antisepsis may be attained more or less successfully by the administration of yeast or of lactic acid ferments together with suitable diet. The nuclein of yeast may be of some value in promoting a leukocytosis. It has not been shown, however, that the polymorphonuclear leukocyte increase caused by nuclein has made phagocytosis more active.
To this process Metchnikoff gave the name of phagocytosis, and he recognised two forms of phagocytes: the microphages, which are the polymorpho-nuclear leucocytes of the blood; and the macrophages, which include the larger hyaline leucocytes, endothelial cells, and connective-tissue corpuscles.
The first indication is the immediate and complete removal of the infected material. The wound must be freely opened, all blood-clot, discharge, or necrosed tissue removed, and the area disinfected by washing with sterilised salt solution, peroxide of hydrogen, or eusol. Stronger lotions are to be avoided as being likely to depress the tissues, and so interfere with protective phagocytosis.
Must we however with an eminent bacteriologist declare any explanation of growing old insufficient that does not take account of phagocytosis? We do not feel qualified to settle the question.
#Immunity.# Some persons are insusceptible to infection by certain diseases, from which they are said to enjoy a natural immunity. In many acute diseases one attack protects the patient, for a time at least, from a second attack acquired immunity. Phagocytosis.
There has been not a little dispute, however, as to the method by which they carry on the conflict. This idea gave rise to the theory of phagocytosis, and the corpuscles were consequently named phagocytes. The study of several years has, however, made it probable that this is not the ordinary method by which the corpuscles destroy the bacteria.
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