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Updated: May 18, 2025
The negative results of tuberculin tests may assist in the differentiation from tuberculous disease, but the more certain means of excising one of the suspected glands and submitting it to microscopical examination should be had recourse to. The sections show proliferation of endothelial cells, the formation of numerous giant cells quite unlike those of tuberculosis and a progressive fibrosis.
The process itself was most simple, consisting essentially of nothing more than the treatment of a microscopical section with a solution of carmine. But the result was wonderful, for when such a section was placed under the lens it no longer appeared homogeneous.
She learned to watch herself carefully, and when with him to preserve a discreet attitude that should not offend him. No curious looks, and no questions. But this was not always easy, so she asked leave to assist him in his work, and sometimes drew in larger size the designs that he made for his microscopical studies. In this way the time passed rapidly.
My attention was called to it, by observing the footsteps of the mules stained a pale red, as if their hoofs had been slightly bloody. I at first thought that it was owing to dust blown from the surrounding mountains of red porphyry; for from the magnifying power of the crystals of snow, the groups of these microscopical plants appeared like coarse particles.
The things which are great, which have significance, which have meaning to the human mind are lost in such a world. Life itself becomes infinitesimal. There is something moving in a tiny ebullition of dust along the white trail. It looks so small. It moves so slowly, crawling, seemingly, at a snail's pace. It is almost microscopical in the vastness. Yet it is only these things by comparison.
Our first national observatory rose at Greenwich, and modern astronomy began with the long series of observations which immortalized the name of Flamsteed. His successor, Halley, undertook the investigation of the tides, of comets, and of terrestrial magnetism. Hooke improved the microscope and gave a fresh impulse to microscopical research.
In his rural walks he can not only appreciate the beneficence of Nature, and the beauties and harmonies of the vegetable kingdom in their exterior aspect, but he can also penetrate into the hidden processes which are going on in the roots, trunks, and leaves of plants and flowers, and contemplate the numerous vessels through which the sap is flowing from their roots through the trunks and branches; the millions of pores through which their odoriferous effluvia exhale; their fine and delicate texture; their microscopical beauties; their orders, genera, and species, and their uses in the economy of nature.
He drew from his waistcoat pocket a small, flat jeweler's case and took out a delicate machine resembling the complicated interior of a watch. "Now," he said, "with this tiny machine concealed in my waistcoat pocket, I walk up to any man and, by turning a screw like the stem of a watch, open the microscopical receiver. Into the receiver flow all psychical emanations from that unsuspicious citizen.
In addition, it may be as well to remember that death sometimes occurs suddenly in exophthalmic goitre, hypertrophy of the thymus, and in Addison's disease. In some cases of sudden death nothing has been found post mortem, even when the autopsy has been made by skilled observers, and the brain and cord have been submitted to microscopical examination. Cadaveric appearance; ashy white colour.
On November 23rd, 1664, the President of the Royal Society was "desired to sign a licence for printing of Mr. Hooke's microscopical book." At this time the book was mostly printed, but it was delayed, much to Hooke's disgust, by the examination of several Fellows of the Society.
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