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Updated: July 3, 2025
While angina pectoris and edema of the lungs were not infrequent causes of death in men, it was a rare cause of death in women. Dyspnea is a frequent symptom, and one for which many patients seek medical advice. A constant systolic blood pressure of over 200 shows a probability that the patient will ultimately die either of uremia or of apoplexy.
The following hypothesis is based upon Fischer's edema theory of glaucoma and the relation of the circulation of the eye and orbit and that of the nose and the accessory sinuses, the minute anatomy of which is not as yet thoroughly understood.
Other cures for which van Helmont vouched included a man who was exceedingly fat; he touched the stone every morning with the tip of his tongue and very speedily lost weight. Van Helmont's own wife was cured of a marked edema of the leg. Similarly, a servant maid who had had severe attacks of erysipelas which were "badly cured," and the leg leaden colored and swollen, was cured almost immediately.
When there is hypotension, or when the diastolic pressure is high and the venous pressure is high, and when there is edema or effusion, watery catharsis should be caused only after due consideration, and always with a careful watching of the effect on the heart and blood pressure. The blood pressure is lowered by such catharsis, and the heart is often slowed.
He was on digitalis and several other heart medications plus diuretics, but in no way was his condition under control. He had severe edema in the feet and legs with pitting, and fluid retention in the abdominal region caused a huge paunch that was solid to the touch not soft and squishy like fatty tissue.
On the other hand, Tristiano seems to have proved that calcium chlorid is capable of lowering ocular tension and clinically may be used as an adjuvant in the treatment of glaucoma for this purpose, largely because he believes that he has proven that it facilitates the absorption of edema.
On the other hand, if he has edema or dropsy, or if the heart showed signs of weakness, large amounts of liquids should certainly not be given, and in such cases it is better that he receive small quantities of milk if that agrees, rather than large quantities of skimmed milk. The amount of water should also be fitted to the circulatory ability and the condition of the kidneys.
The magnificent experimental work of this investigator has shown that edema is nothing more or less than an increased capacity of the protein colloid tissues for water; that the most important factor leading to this increased hydration capacity is an abnormal production or accumulation of acid content, effected by those agencies which are instrumental in causing sclerosis and an increase of blood pressure.
They press against the root of the iris and the equator of the lens, forcing them forward. There is edema of the ureal tract, apparently from transudation of serum. Many small, and sometimes rather large hemorrhages may occur. There is but little small cell infiltration, indicating almost total absence of what is ordinarily recognized as true inflammation.
Fischer in a personal letter says: "You have two possibilities for the production of glaucoma with sinus disease: A toxic factor due to poisons being carried into the eye; and second, interference with a proper blood supply to the eye through compression of the efferent or afferent blood vessels supplying the eye from edema of the tissues about the eye consequent upon the sinus infection.
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