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Updated: June 9, 2025
Although I say the system may at any time be made to feel the febrile attack of cow-pox, yet I have a single instance before me where the virus acted locally only, but it is not in the least probable that the same person would resist the action both of the cow-pox virus and the variolous. Elizabeth Sarfenet lived as a dairymaid at Newpark farm, in this parish.
An hospital for gratuitous vaccination, founded by the Prefect of the department of La Seine, is now open for the continual treatment of the cow-pox, and the distribution of the matter to all parts of France.
"A very good infection to take, Agnes," replied the master, with a smile of thorough pleasure, "and one that will do more for you than the cow-pox. Come to me as often as you can and as you like. I think I shall be able to tell you some things to make you happier." "'Deed, sir. I'm in no want o' happiness! O' that I hae full mair nor I deserve; but I want a heap for a' that.
Fry, Mr. Darke, Mr. Tierny, Mr. H. Jenner, and others, there were many whom they inoculated ineffectually with variolous matter, who had gone through the cow-pox many years before this trial was made. It has been imagined that the cow-pox is capable of being communicated from one person to another by effluvia without the intervention of inoculation.
Hicks, having mentioned your wish to be informed of the progress of the inoculation here for the cow-pox, and he also having taken the trouble to transmit to you my minutes of the cases which have fallen under my care, I hope you will pardon the further trouble I now give you in stating the observations I have made upon the subject.
The cow-pox is nothing else than small-pox modified in character, diminished in severity by passing through the system of the animal; but giving, when introduced into the system, a safeguard against natural small-pox at least as complete as that furnished by the inoculated disease.
7th: A perceptible vesicle: this evening the patient became a little chilly; no pain or tumour discoverable in the axilla. 8th: Perfectly well. 9th: The same. 10th: The vesicle more elevated than I have been accustomed to see it, and assuming more perfectly the variolous character than is common with the cow-pox at this stage.
The great Dr Jenner, the discoverer of cow-pox as a preventative of small-pox, strongly advocated the absolute necessity of every person being re-vaccinated once every seven years, or even, oftener, if there was an epidemic of small-pox in the neighbourhood. Are you not likely to catch not only the cow-pox, but any other disease that the child has from whom the matter is taken?
In a word, is it not impossible for the cow-pox, whose ONLY manifestation appears to consist in the pustules CREATED BY CONTACT, to produce ITSELF by effluvia? In the course of a late inoculation I observed an appearance which it may be proper here to relate.
On the 14th day of May, 1796, the day marks an epoch in the Healing Art, and is not less worthy of being kept as a national thanksgiving than the day of Waterloo the cow-pox matter or pus was taken from the hand of one Sarah Holmes, who had been infected from her master's cows, and was inserted by two superficial incisions into the arms of James Phipps, a healthy boy of about eight years of age.
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