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Updated: June 2, 2025
Roux, after adverting to the labors of Behring, Ehrlich, Boer, Kossel, and Wasserman, described in detail the methods that had been developed at the Pasteur Institute for the development of the curative serum, to which Behring had given the since-familiar name antitoxine.
The effect on the horse is the same as if the animal had the disease. Its cells react and produce a considerable quantity of the antitoxine which remains in solution in the blood of the animal. This is not theory, but demonstrated fact.
Then it is known that Dr. Yersin, with the collaboration of his former colleagues of the Pasteur Institute, has developed, and has used with success, an antitoxine from the microbe of the plague which recently ravaged China. Dr.
"You have given it to the child?" she asked. "Yes, just a few minutes ago," he answered. "We only left Edward's Bay at sunrise. The man is getting well. I was told of this case and went up to Sammy's for the antitoxine." "But it was the last you had!" she cried, "and Atkins has only been able to start this morning for more, and the wind is very bad for him. It may be days before he returns."
John's and buy all the antitoxine you can get hold of, any amount, barrels of it, if it comes that way. And bring a doctor back with you. Promise him all the money he wants. And get a nurse, or a couple of them, or a dozen. Regular trained nurses, you understand. Yes, it's antitoxine I want. Write it down. It's the stuff they use for diphtheria. Then get back here at once.
It will be clear that to obtain the antitoxine we must depend upon some natural method for its production. We do not know enough of the chemical nature of the antitoxines to manufacture them artificially. Of course we can not deny the possibility of their artificial production, and certain very recent experiments indicate that perhaps they may be made by the agency of electricity.
He whispered this as he pointed to the bed where the doctor was lying. "The boy is getting well," answered the parson, in a low voice. "He had a large dose of antitoxine and it is beginning to show its effect." "Ah? Just so," said Daddy, weakly. Then he looked around the room again, quite helplessly. "Is there anything that I could do?" he asked in a general way. "Nothing, Daddy," I said.
It is not easy at the present stage to sift that which is tentative from that which will be permanent; but so great an authority as Behring does not hesitate to affirm that today we possess, in addition to the diphtheria antitoxine, equally specific antitoxines of tetanus, cholera, typhus fever, pneumonia, and tuberculosis a set of diseases which in the aggregate account for a startling proportion of the general death-rate.
It is to Pasteur, the immortal chemist, that we owe this theory, as well as that of the attenuation of viruses both of more than theoretical import, since they have given us aseptic surgery, the power of frequently preventing hydrophobia, the antitoxine treatment of diphtheria, and the ability to stay the hand of Death in the form of many a stalking pestilence.
"There is diphtheria at Sweetapple Cove, and a doctor there who is nearly dead with it, I believe. I've sent our mate for all the antitoxine he can buy, and he's driving around to all the druggists in the place. We also want a nurse, several nurses, all you can get. I'm keeping steam up and will start the minute you're ready." "And the remuneration," suggested Mr. Simpson.
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