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Until its internal effects are better known, caution is advised as to its very widespread application, although Herr Schroter has taken a gramme with only some apparent increase of peristalsis and appetite. Lancet. The illustration represents an autopsy table placed in the Coroner's Department of the New York Hospital, designed by George B. Post and Frederick C. Merry.

The benefits of pain are especially manifested in the urgent muscular actions by means of which the body moves away from physical injury; obstructions of the hollow viscera are overcome; rest is compelled in the acute infections the infected points are held rigidly quiet, the muscles of the abdomen are fixed, and harmful peristalsis is arrested in peritonitis; while there is absolutely no pain in the diseases or injuries which affect those regions of the body in which in the course of evolution no pain receptors were placed, or in those diseases in which muscular inhibition or contraction is of no help.

It is the nature of the muscular structures to grow if exercised, and there is no reason to doubt that the stomach and intestinal muscles respond to this stimulus. Bulk is especially necessary in the intestinal canal, to supply a certain amount of irritative stimulation, for the purpose of exciting peristalsis.

At first this is felt over the entire abdomen, but it is more marked near the navel than elsewhere. After about twenty-four hours it becomes localized in the region of the cecum. The pain is colicky or spasmodic in character, showing that it is due to peristalsis; food of any kind increases the peristalsis; hence the pain becomes more severe after feeding.

And even if it did suspend peristalsis for a few minutes, is it not a fact that other natural functions can be suspended for a much longer period, only to be resumed with unabated vigor?

The drugs stimulate peristalsis of the small intestine; each wave from the small intestine breaks on the walls of the cecum, for the colon is loaded with fecal accumulations so that the onrushing contents of the small intestine can not be received by the colon; hence the force of the whole peristaltic impact is spent on the cecum, which must endanger the integrity of the mucosa as well as the musculature.

In appendicitis only very small quantities of water are to be given by mouth at first, until the acute symptoms have subsided. Large quantities of fluid may excite violent peristalsis with resulting pain. In all eases of nausea, give nothing by mouth, not even water, until the nausea is gone.

When the inflammation starts causing increased bowel contractions peristalsis there is a breaking down of the walls of this fecal ring resulting in complete obstruction. The ineffectual bowel contractions then serve to irritate and inflame the affected part still more.

The starch contained in the gruel will always create gas in these cases and stimulate peristalsis; the gas inflates the cecum and drives the contents of the bowels into the abscess cavity; this sets up secondary inflammation. The meat juice and wine could have been left out to the patient's betterment.

Claudication also may result from the impaired circulation. The emotions may cause an inhibition of the digestive secretions and of intestinal peristalsis. This means that the digestive processes are arrested, that putrefaction and autointoxication will result, and that still further strain will thus be put upon the organs of elimination.