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The skin-fibre layer forms the corium and the motor organs the skeleton and the muscular system. From the gut-fibre layer are developed the vascular system, the muscular wall of the gut, and the sexual glands. The manner in which these different systems of organs arise from the secondary germinal layers is essentially the same from the start in man as in all the other Vertebrates.

#Structure of Skin.# The skin is composed of a superficial cellular layer the epidermis, and the corium or true skin. The epidermis is differentiated from without inwards into the stratum corneum, the stratum lucidum, the stratum granulosum, and the rete Malpighii or germinal layer, from which all the others are developed.

... -ubi revenisses domum, Cincticulo praecinctus in sella apud magistrum adsideres; Si, librum cum legeres, unam peccavisses syllabam, Fieret corium tam maculosum, quam est nutricis pallium-. I. XIV. The Oldest Italo-Greek Calendar I. XIV. The Oldest Italo-Greek Calendar I. XV. Plastic Art in Italy II. VIII. Building II. VIII. Building I. XV. Earliest Hellenic Influences I. VII. Servian Wall

The corium or true skin consists of connective tissue, in which ramify the blood vessels, lymphatics, and nerves. That part of the corium immediately adjoining the epidermis is known as the papillary portion, and contains the terminal loops of the cutaneous blood vessels and the terminations of the cutaneous nerves.

#Corns.# A corn is a localised overgrowth of the horny layer of the epidermis, which grows downwards, pressing upon and displacing the sensitive papillæ of the corium. Corns are due to the friction and pressure of ill-fitting boots, and are met with chiefly on the toes and sole of the foot.

It may feel inert or it may be inflamed. The skin is a beautiful and complex structure. It is made up of an outer layer called the epidermis and an inner layer, the true skin or corium, which rests upon a subcutaneous layer, composed principally of fat and connective tissue. The epidermis is divided into four layers.

Immediately under the thin corium, and closely connected with it, we find a thin muscle tube, as in the worms. On the other hand, the Ascidia has a centralised heart, and in this respect it seems to be more advanced than the Amphioxus. On the ventral side of the gut, some distance behind the gill-crate, there is a spindle-shaped heart.

Disturbance of the sight shortly intervened, associated with aphonia. The sensibility of the whole body, with the exception of the face, was greatly impaired, and there was true gangrene of the corium. A younger sister of the patient was similarly affected with symptoms of hysteria, hemianesthesia, etc.

Of the four original gill-arches of the mammals the first lies between the primitive mouth and the first gill-cleft. At the outer surface of the latter is formed from the cellular matter of the corium, as covering or accessory bone, the permanent bony lower jaw.

2 Et si qui ex eis regi Angliæ & ei rebelles fuerint, & tributum & alia iura regis Angliæ per manum eius soluere noluerint, & à fidelitate regis Angliæ recesserint, ipse eos iusticiet & amoueat. Et si eos per se iusticiare non poterit, constabularius regis Angliæ, & familia sua de terra ilia iuuabunt eum ad hoc faciendum, cùm ab ipso fuerint requisiti, & ipsi viderint quòd necesse fuerit. Et propter hunc finem reddet prædictus rex Conaciæ domino regi Angliæ tributum singulis annis, scilicet de singulis decem animalibus vnum corium placabile mercatoribus, tam de tota terra sua, qu