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Updated: May 28, 2025
In old subjects used for dissection or surgical purposes, it is very evident that in the ones which have suffered from chronic lymphangitis there exists an excessive amount of sub-facial connective tissue, making subcutaneous neurectomies quite difficult in some instances. A sequel of chronic lymphangitis is a condition known as elephantiasis.
In Natural Therapeutics every one of the various methods of treatment is supplemented and assisted by all the others. The manipulative schools of healing maintain that practically all disease is caused by mechanical abnormalities of the spinal column or of muscles, ligaments and other connective tissues, due to abnormal strain or injury.
On the other hand, some arteries, especially if the calcareous deposits are considerable, may become weakened in spots and dilation may occur, causing either smaller or larger aneurysms. Histologically the disease is a connective tissue formation beginning first as a round-cell infiltration in the subendothelial layer of the intima.
Cellulitis is an acute affection resulting from the introduction of some organism commonly the streptococcus pyogenes into the cellular connective tissue of the integument, intermuscular septa, tendon sheaths, or other structures.
These processes are accompanied by changes in the endothelium of the vessel walls, which result in an increased formation of lymph, which transudes into the meshes of the connective tissue giving rise to an inflammatory œdema, or, if the inflammation is on a free surface, forming an inflammatory exudate.
A similar deformity of the thumb is sometimes met with. Microscopical examination of the muscles shows that, prior to the deposition of lime salts and the formation of bone, there occurs a proliferation of the intra-muscular connective tissue and a gradual replacement and absorption of the muscle fibres.
If the blood pressure is low, or not higher than is best for the patient, such treatment would be inadvisable. If, from the supposed cause, iodid seems to be indicated, it should be given in small doses and continued for some time. It is often wise, however, to give small doses, as 0.10 or 0.20 gm. Iodid tends to prevent the progress of connective tissue formation.
The corium or true skin consists of connective tissue, in which ramify the blood vessels, lymphatics, and nerves. That part of the corium immediately adjoining the epidermis is known as the papillary portion, and contains the terminal loops of the cutaneous blood vessels and the terminations of the cutaneous nerves.
Capillary loops grow into the coagulum, and migrated leucocytes from the adjacent blood vessels destroy the red corpuscles, and are in turn disposed of by the developing fibroblasts, which by their growth and proliferation fill up the gap with young connective tissue. It will be evident that this process only differs from healing by primary union in the amount of blood-clot that is present.
All the coats are thickened, chiefly by an increased development of connective tissue, and in some cases changes similar to those of arterio-sclerosis occur. The walls of varicose veins are often exceedingly brittle. In some cases the thickening is uniform, and in others it is irregular, so that here and there thin-walled sacs or pouches project from the side of the vein.
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