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Cellulitis is an acute affection resulting from the introduction of some organism commonly the streptococcus pyogenes into the cellular connective tissue of the integument, intermuscular septa, tendon sheaths, or other structures.

It most frequently originates from fascia, intermuscular connective tissue, periosteum, bone-marrow, and skin, and forms a rounded or nodulated tumour which appears to be encapsulated, but the capsule merely consists of the condensed surrounding tissues, and usually contains sarcomatous elements.

The extension of the ossification into the synovial reflection and capsular ligament adds a collar or "lip" of new bone, known as "lipping" of the articular margins, and also into other ligaments, insertions of tendons and intermuscular septa giving rise to bony outgrowths or osteophytes not unlike those met with in the neuro-arthropathies.

It is met with also in the subcutaneous and intermuscular cellular tissue, and in the abdominal wall, where it sometimes attains considerable dimensions. Various forms of fibroma are met with in the mamma and are described with diseases of that organ. The fibrous overgrowths in the skin, known as keloid and molluscum fibrosum, and those met with in the sheaths of nerves, are described elsewhere.

A physics of human behaviour becomes possible with the aid of these concepts of endocrine regulation of intravisceral pressure, and intervisceral equilibrium, an intramuscular pressure and an intermuscular equilibrium, with the brain as the shifting fulcrum of the system. The sensation of hunger, as we have seen, serves as good an exemplar as any of this mechanism of the wish.