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Updated: June 18, 2025
After fractures of costal cartilage or of the cartilages of the larynx the cicatricial tissue may be ultimately replaced by bone. Tendons. When a tendon is divided, for example by subcutaneous tenotomy, the end nearer the muscle fibres is drawn away from the other, leaving a gap which is speedily filled by blood-clot.
Under this scab the formation of granulation tissue, its transformation into cicatricial tissue, and the growth of epithelium on the surface, go on until in the course of time the crust separates, leaving a scar. Healing by Blood-clot.
Treatment. The first indication is to purify the whole extent of the wound, and to remove any foreign body or blood-clot that may be in it. It is usually necessary to enlarge the wound, freely dividing injured fasciæ, paring away bruised tissues, and purifying the whole wound-surface.
Suppuration may occur in the vicinity of an aneurysm, and the aneurysm may burst into the abscess which forms, so that when the latter points the pus is mixed with broken-down blood-clot, and finally free hæmorrhage takes place. It has more than once happened that a surgeon has incised such an abscess without having recognised its association with aneurysm, with tragic results.
His hands flew forward with the fall, and I saw that what I had taken for a red cloth was a monstrous wound, which had left a great gap in his neck, from which a dark blood-clot hung, like an epaulette upon his shoulder. 'My God! I cried, as I sprang to his aid. 'And I thought that you were drunk! 'Not drunk, but dying, said he.
Where the granulations are vascular and bleed easily, it becomes sanious from admixture with red corpuscles; while, if a blood-clot be broken down and the debris mixed with the pus, it contains granules of blood pigment and is said to be "grumous." The odour of pus varies with the different bacteria producing it.
The first indication is the immediate and complete removal of the infected material. The wound must be freely opened, all blood-clot, discharge, or necrosed tissue removed, and the area disinfected by washing with sterilised salt solution, peroxide of hydrogen, or eusol. Stronger lotions are to be avoided as being likely to depress the tissues, and so interfere with protective phagocytosis.
For an instant, with an evil leer the sun peered through the naked woods of Vincennes, sank like a blood-clot in the battery smoke, lower, lower, into the blood-soaked plain. When midnight sounded from the belfry of St. Sulpice the gates of Paris were still choked with fragments of what had once been an army.
In subcutaneous wounds, for example tenotomy, in amputation wounds, and in wounds made in excising tumours or in operating upon bones, the space left between the divided tissues becomes filled with blood-clot, which acts as a temporary scaffolding in which granulation tissue is built up.
In the corpus luteum the lutein is contained in the cells, not in a blood-clot. Chemical investigation shows that the lutein of the corpus luteum is almost if not quite identical with the colouring matter of the yolk in birds and reptiles. Physiol. The difference, if it exists, is very slight, and it is evident that one compound could easily be converted into the other.
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