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Updated: May 20, 2025
What concerns us now is its internal secretion or secretions. One of them is known as lutein and it has never been chemically isolated in its pure form. The existence of lutein, like the existence of electricity, is an inference, something we are sure is there because of its effects. It originates in a remarkable part of the ovary, the corpus luteum.
The presence of this hormone might cause the follicular cells to behave as though the ovum was still present in the follicle, so that they would persist and not die and be absorbed. But this leaves the question, what is lutein and why is it secreted? Lutein is a colouring matter sometimes found in blood-clots, and probably derived from haemoglobin.
In the corpus luteum the lutein is contained in the cells, not in a blood-clot. Chemical investigation shows that the lutein of the corpus luteum is almost if not quite identical with the colouring matter of the yolk in birds and reptiles. Physiol. The difference, if it exists, is very slight, and it is evident that one compound could easily be converted into the other.
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