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Updated: June 16, 2025
That is one of the effects of the mydriatic alkaloids, of which this is one. The ancients were familiar with several of its peculiar properties, as they knew of the closely allied poison hemlock. "Many of the text-books at the present time fail to say anything about the remarkable effect produced by large doses of this terrible alkaloid.
It was Unamuno himself who once said that the Basque is the alkaloid of the Spaniard. The saying is true, so far as it goes. But it would be more accurate to say "one of the two alkaloids."
The physiological action of coffee depends on the presence of the alkaloid caffeine, which varies from 0.6 percent in the Arabian berry to 2 percent in that of Sierra Leone. Again, the aromatic oil, caffeine, which is developed by roasting, increases in quantity the longer the seeds are kept.
Assuming that the whole of this quantity was injected the amount taken would be forty five-hundredths, or about one twelfth of a grain. The ordinary medicinal dose of strophanthin is one five-hundredth of a grain. "'I also found in the body appreciable traces of morphine the principal alkaloid of opium from which I infer that the deceased was a confirmed opium-smoker.
If it stands too long, or is boiled, more indeed is got out of it, but an astringent, disagreeable drink is the result. The boiling of coffee extracts all its oil and alkaloid too, and, when it is drunk with the grounds, allows the whole nutriment to be available. Even when strained, it is clearly more economical than tea." Roasted coffee is a powerful deodorizer, also.
It is true that the consequences of excessive tea drinking are not as severe as those from over-indulgence in ardent spirits, but the pernicious effects of the constant drinking of strong infusions of tea justify us in calling the practice a serious menace to health. Tea leaves contain from 2 to 4 per cent. of caffeine, or theme, which is an alkaloid, and always found in combination with tannin.
"That's our friend Bridgers," said Milsom, "he's all lit up with the alkaloid of Enythroxylon Coca Well, Bridgers, nearly finished?" "Huh!" grunted the man without turning. Milsom shrugged his shoulders. "We must let him finish what he's doing. He is quite oblivious to the presence of anybody when he has these fits of industry.
He consequently modified his formula, and gave the following as the composition of atropine; C H NO . Liebig's amended analysis was afterward confirmed by Planta, who further showed that the alkaloid itself melted at 194 deg. F., and its double gold salt at 275 deg. F. It is worthy of remark that the first figure was considered correct until my researches proved the contrary.
"What is it?" we asked as he held the tube up critically to the light. "I can't be sure yet," he answered slowly. "I thought at first that it was some alkaloid. I'll have to make further tests before I can be positive just what it is. If I may retain this sample I think that with other clues that I have discovered I may be able to tell you something definite soon."
"I don't see any foreign crystals on the surface," said he; "but we had better make a solution and go to work systematically. If it contains any poison we may assume that it will be some alkaloid, though I will test for arsenic too. But a man of Weiss's type would almost certainly use an alkaloid, on account of its smaller bulk and more ready solubility.
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