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The major portion of help in the colony, at this period, was of this class, although a few Negroes were brought to Virginia by 1619, and approximately a score are listed in the muster of 1625.

He was soon lost to medicine, but in 1625, Santorini, known to science as Sanctorius, published a curious book, called "Commentaries on Avicenna," in which he figured a variety of similar instruments, called "pulsilograms." We owe to him some of the first accurate studies of diet, and also the discovery of the insensible perspiration, but his pulsilogram was soon forgotten.

Smith complains that the play-writers had appropriated his adventures, but does not say that his own character had been put upon the stage. In Ben Jonson's "Staple of News," played in 1625, there is a reference to Pocahontas in the dialogue that occurs between Pick-lock and Pennyboy Canter: Pick. A tavern's unfit too for a princess. P. Cant.

In 1625 Christian IV., king of Denmark, entered the war as leader on the Protestant side, only to yield to the perseverance of Tilly, the general of the Catholic armies, and to the genius of Wallenstein, the representative of Emperor Ferdinand; and to retire in 1629, leaving north Germany more completely than before at the mercy of the emperor and of the Catholic party.

Hist. vol. vi. p. 353 Journ. 7th July 1625. Charles gave them a gracious and a compliant answer to all their remonstrances. He was, however, in his heart, extremely averse to these furious measures.

Occasionally he occupied a leisure or a rainy day with a Journal, parts of which have been preserved; but he set down in it few of the terrible events here related, probably because they were of too painful a nature to be recorded. He died in 1625 at the early age of thirty-five. But to go back. A few days after the tragical events at Hoghton Tower, the whole village of Whalley was astir.

Shortly afterwards he was made a councillor, and in 1625 secretary of state of the colony. In the Indian war, which began with the massacre in 1622, he was appointed general, and in 1629 received lands in the Pamunkey Neck for valuable military service. Active and fearless, he engaged with great success in the trade for furs in the bay, and was recognized as the foremost man in Virginia.

By the treaty of Southampton, September 17, 1625, an offensive and defensive alliance was concluded with the States-General; and Charles contented himself with a demand that the States should within eighteen months bring to justice those who were responsible "for the bloody butchery on our subjects."

William Laud, who afterwards became Archbishop of Canterbury, began to exert his influence upon the religious life of both England and Scotland during the closing years of James's reign, but it was in the reign of Charles the First, who succeeded his father in 1625, that he came before the world in his sudden and so unfortunate greatness.

Shortly afterwards, Charles the First having succeeded to the throne in 1625, Harvey became one of the king's physicians; and it is much to the credit of the unfortunate monarch who, whatever his faults may have been, was one of the few English monarchs who have shown a taste for art and science that Harvey became his attached and devoted friend as well as servant; and that the king, on the other hand, did all he could to advance Harvey's investigations.