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Updated: May 15, 2025
In this way a great division was made between the two functions of the body, and two sets of organs: in the vascular system, the heart and arteries and abdominal organs, life was controlled by the vital spirits; on the other hand, in the nervous system were elaborated the animal spirits, controlling motion, sensation and the various special senses.
Now, it goes without saying, if these data are correct, or even only partly correct, that part of the treatment of the increased intra-ocular pressure state must be constitutional in that the vascular pressures should be lowered in order that the beneficial effect of their relationship to the intra-ocular pressure shall be established.
I repeated, with increasing scorn. "Strikes me, you can do pretty well as you like on this station." "Bea n't Oi a-diewin' my diewty?" he asked in wavering expostulation the point now settling in the vascular tissues. "It's in the blood, right enough," I retorted, with insolent frankness, and still regarding him out of the comer of my eye.
The baby throws his arms about, kicks his legs, rolls his eyes. In these movements arising from internal activities which, we can only state, relate to vascular distribution, neuronic relations, visceral and endocrinic activities, is the germ of the impulse to activity which it is the function of society and the individual himself to shape into organized useful work.
Now if adrenalin caused these changes merely as a metabolic phenomenon and not as a "work" phenomenon, then the injection of adrenalin into the carotid artery of a crossed circulation dog would cause no change in its circulation and its respiration, since the brain thus injected is in exclusive vascular connection with the body of another dog.
That bulk would actually increase by use of the forceful medicine is likely; but that the increase would be dropsical I think is unquestionable. The dropsy of debility is due to a loss of tone of the vascular system; the walls of the vessels become thinner and therefore dilate.
Once more, the subsequent appearance of the vascular layer between these mucous and serous layers, as they have been named, admits of a like interpretation. And in this and the various complications which now begin to show themselves, we may see coming into play that general law of the multiplication of effects flowing from one cause, to which the increase of heterogeneity was elsewhere ascribed.
When the quiescence of the arterial system is not owing to defect of stimulus as above, but to the defective quantity of sensorial power, as in the commencement of nervous fever, or irritative fever with weak pulse, a great torpor of this system is quickly induced; because both the irritation from the stimulus of the blood, and the association of the vascular motions with each other, continue to excite the arteries into action, and thence quickly exhaust the ill-supplied vascular muscles; for to rest is death; and therefore those vascular muscles continue to proceed, though with feebler action, to the extreme of weariness or faintness: while nothing similar to this affects the locomotive muscles, whose actions are generally caused by volition, and not much subject either to irritation or to other kinds of associations besides the voluntary ones, except indeed when they are excited by the lash of slavery.
The periosteum is abnormally thick and vascular, the superficial layers of the bone become injected and porous, and the bones, as a whole, are thickened. When the whole thickness of the soft tissues is destroyed by the ulcerative process, the area of bone that comes to form the base of the ulcer projects as a flat, porous node, which in its turn may be eroded.
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