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Updated: May 9, 2025


Nigel endeavoured to explain, but the idea of thieves had taken possession of the old man's pineal gland, and he kept coughing and screaming, and screaming and coughing, until the gracious Martha entered the apartment; and, having first outscreamed her father, in order to convince him that there was no danger, and to assure him that the intruder was their new lodger, and having as often heard her sire ejaculate "Hold him fast ugh, ugh hold him fast till I come," she at length succeeded in silencing his fears and his clamour, and then coldly and dryly asked Lord Glenvarloch what he wanted in her father's apartment.

The pineal, the ghost of a once important third eye at the back of our heads, still harks back in its function to a regulation of our susceptibility to light, and its effect upon sex and brain. So it becomes one of the significant regulators of development, with an indirect hastening or retardation of puberty and maturity according as it works in excess, or too indolently.

Clinical observations emphasize that in childhood it is the chief brake upon the other glands of internal secretion which would hasten development and differentiation, checking them perhaps for a given time and so profoundly influencing growth. The pineal is another gland which has been credited with similar abilities and a like holding-the-reins-tight-in-childhood function among the cells.

That it might perhaps be, in a sense, a gland of internal secretion was a despised theory. Then a classic case, the most extraordinary and curiosity-piquing sort of case, with symptoms involving the pineal gland, in a boy, was reported by the German neurologist, Von Hochwart. That boy provoked a little army of researches.

What is one to think of a child with two heads? without deformity apart from this? Some say that it has two souls because it is provided with two pineal glands, with two corpus callosum, with two sensorium commune. Others reply that one cannot have two souls when one has only one chest and one navel.

To this convenient little central office he relegated it; and he describes in a way that may to-day well provoke a smile the movements that the soul imparts to the pineal gland, making it incline itself in this direction and in that, and making it push the "animal spirits," the fluid contained in the cavities of the brain, towards various "pores."

It is probable that these thymus and pineal effects are indirect through their action upon the sex glands. For in the types with persistent juvenile thymus there occurs a maldevelopment of the sex glands, while in those with early pineal recession the sex glands bloom simultanously with the appearance of adolescent hair and mental traits.

For, since menstruation is so closely connected with the phases of the moon and the tides, the rhythmicity of the posterior pituitary may be traced to the days when the pineal was an eye at the top of the head, and in direct relation with the pituitary. Menstruation has been said to be a miniature labor. It is not that as much as it is a miniature abortion. It is an effort of nature still-born.

Modern knowledge of these chemical substances, circulating in the blood, and affecting every cell of the body, dates back scarce half a century. But already the paths blazed by the pioneers have led to the exploration of great countries. The thyroid gland, the pituitary gland, the adrenal glands, the thymus, the pineal, the sex glands, have yielded secrets.

As a consequence, to hold the sex stimulating glands in check, there had to appear others, restraining them and so preventing sex precocity. These are the thymus and pineal. So closely are they all related that insufficient action of the thyroid, pituitary or adrenals may cause atrophy of the ovaries and uterus, with abolition of genital function.

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