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Updated: June 11, 2025
The lesions in infancy epiphysitis, bossing of the skull, and craniotabes have been referred to in the chapter on inherited syphilis. Epiphysitis or Syphilitic Perichondritis. The first of these terms is misleading, because the lesion involves the ossifying junction and the shaft of the bone, and the epiphysis only indirectly.
Its value, however, is not so great as in kidney lesions, and if it causes hardship to the patient it should not be continued rigorously. On the other hand, large amounts of salt should of course be interdicted.
The more normal the chemical composition of the blood, and the more free the tissues are from clogging impurities, poisons and mechanical obstructions, such as lesions of the spinal column, the more abundant will be the liberation and the available supply of vital energy.
The right ventricle hypertrophy caused by mitral lesions has already been sufficiently discussed. The right ventricle also hypertrophies in emphysema, after repeated or prolonged asthma attacks, perhaps generally in neglected pleurisies with effusion, in certain kinds of tuberculosis, and whenever there is increased resistance in the lung tissue or in the chest cavity.
Among lesions of the viscera, mention should be made of gumma of the testis, which causes the organ to become enlarged, uneven, and indurated. This has even been observed in infants a few months old.
Among other consequences of an alcoholic inheritance which have been traced by careful observers are: Morbid changes in the nerve centers, consisting of inflammatory lesions, which vary according to the age in which they occur; alcoholic insanity; congenital malformations; and a much higher infant death rate, owing to lack of vitality, than among the children of normal parents.
But you greatly misunderstand me if you imagine that I believe in her final dissolution, because I point out her wounds and her lesions. I believe in the life which ceaselessly eliminates hurtful substances, which makes new flesh to fill the holes eaten away by gangrene, which infallibly advances toward health, toward constant renovation, amid impurities and death."
Still, I could not hide from myself that he was a changed man since that voyage in search of health from which he had just returned. His mother talked in her humdrum way about heart disease; and his father, taking up the strain, bored us about organic lesions, till we almost wished he had a lesion himself.
It is not sufficiently recognized that a subacute arthritis, recurring tonsillitis, open and concealed infections in the mouth, and even a condition of the system with acute, changeable and varying joint and muscle pains may all develop a mild endocarditis, even with subsequent valvular lesions.
It would perhaps be better to consider a slow-going inflammatory process subsequent to acute endocarditis as a subacute endocarditis; and an infective process may persist in the endocardium, especially in the region of the valves, for many weeks or perhaps months, with some fever, occasional chills, gradually increasing valvular lesions and more or less general debility and systemic symptoms.
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