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Updated: May 9, 2025
When the disease is arrested, a process of repair sets in which often results in the bones becoming denser and heavier than normal. In the flat bones of the skull, the absorption may result in the entire disappearance of areas of bone, leaving a membrane which dimples like thin cardboard under the pressure of the finger a condition known as craniotabes.
Craniotabes is recovered from as the child improves in health. Between the ages of three and six months, certain other phenomena may be met with, such as effusion into the joints, especially the knees; iritis, in one or in both eyes, and enlargement of the spleen and liver.
The lesions in infancy epiphysitis, bossing of the skull, and craniotabes have been referred to in the chapter on inherited syphilis. Epiphysitis or Syphilitic Perichondritis. The first of these terms is misleading, because the lesion involves the ossifying junction and the shaft of the bone, and the epiphysis only indirectly.
When the shaft of a long bone is affected, not only deformity, but even fracture may occur. Under these circumstances the humerus and femur appear to be the bones most likely to break; there is an associate deformity of the head, known as "craniotabes," together with pigeon-breast and various spinal curvature.
The term craniotabes is applied when the bone becomes thin and soft, reverting to its original membranous condition, so that the affected areas dimple under the finger like parchment or thin cardboard; its localisation in the posterior parts of the skull suggests that the disappearance of the osseous tissue is influenced by the pressure of the head on the pillow.
#Lesions of Bone in Inherited Syphilis.# Craniotabes, in which the flat bones of the skull undergo absorption in patches, was formerly regarded as syphilitic, but it is now known to result from prolonged malnutrition from any cause. Bossing of the skull resulting in the formation of Parrot's nodes is also being withdrawn from the category of syphilitic affections.
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