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Updated: May 8, 2025


Inoculation was still with us considered very problematical; and, although it had already been intelligibly and urgently recommended by popular writers, the German physicians hesitated to perform an operation that seemed to forestall Nature.

At the same time I inoculated the mother and eldest sister with variolous matter taken from Master H . On the fifth day of their inoculation ALL their arms were inflamed alike; and on the eighth day the eldest of those inoculated from the nurse sickened, and the youngest on the eleventh.

Some time after inoculation, leprosy made its appearance, and the man died a leper on Molokai. Nor was this conclusive, for it was discovered that at the time he was inoculated several members of his family were already suffering from the disease on Molokai.

Certain of these seem intended to secure the complete union of husband and wife; such, for example, are the customs of eating together, of the inoculation of each party with the blood of the other or with some bodily part of the other, and the giving of presents by each to the other.

They have a castle there a castle, something like well, like the old Schloss at Heidelberg. Did you ever hear about or read about Heidelberg University?" But K. D. B. was all abroad now. Gibraltar and Heidelberg were unknown subjects to her, as were also inoculation, Japan, and Kosciusko. Above the G's she was sound; below that point her ignorance was benighted.

Of all the advertisements of small-pox hospitals, inoculation, etc., which appear in the newspapers through the eighteenth century, none is more curious, more comic than this from a Boston paper of 1772: "Ibrahim Mustapha Inoculator to his Sublime Highness & the Janissaries: original Inventor and sole Proprietor of that Inestimable Instrument, the Circassian Needle, begs leave to acquaint the Nobility & Gentry of this City and its Environs that he is just arrived from Constantinople where he has inoculated about 50,000 Persons without losing a Single Patient.

Its immunity is decidedly fleeting, since it was dependent not upon any activity on the part of the body, but upon an artificial inoculation of a material which is rapidly eliminated by secretion.

As the cases of inoculation multiply, I am more and more convinced of the extreme mildness of the symptoms arising merely from the primary action of the virus on the constitution, and that those symptoms which, as in the accidental cow-pox, affect the patient with severity, are entirely secondary, excited by the irritating processes of inflammation and ulceration; and it appears to me that this singular virus possesses an irritating quality of a peculiar kind, but as a single cow-pox pustule is all that is necessary to render the variolous virus ineffectual, and as we possess the means of allaying the irritation, should any arise, it becomes of little or no consequence.

These remedies do not trifle with surface symptoms; they strike at once at removing causes. The ceaseless chagrin of a self-centered life can be removed at once by learning meekness and lowliness of heart. He who learns them is forever proof against it. He lives henceforth a charmed life. Christianity is a fine inoculation, a transfusion of healthy blood into an anæmic or poisoned soul.

The Present Status of the Nitrogen Problem. Yearbook Dept. of Agriculture Reprint, 411. The Search for Leguminous Forage Crops. Yearbook Dept. of Agriculture Reprint, 478. Leguminous Crops. Yearbook Dept. of Agriculture Bulletin, 278. Progress in Legume Inoculation. Yearbook Dept. of Agriculture Bulletin, 315. A Grain for Semi-arid Lands. Yearbook Dept. of Agriculture Bulletin, 139.

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