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Updated: May 1, 2025
The degree of masculine trend in a woman is a crude measure of adrenal domination, the degree of feminine deviation in a man is roughly proportional to the amount of pituitary influences in his make-up. Whether one or the other sex tendency will dominate depends upon the quantity of sex hormone divergence from the ideal normal.
Then heredity of the effect of stimulus took place to some slight degree, and this would occur, according to my theory, only in the presence of the hormone from the ovary in the same condition as that in which the modification was first caused. This would be of course after ovulation, and after hatching of the eggs.
Sometimes, however, the experiential transformation has been sufficiently deep, and shaken the very constitution of his germ-plasm. So family dispositions and traits, national and racial temperaments, are propagated, maintained and varied. Hormone reactions, as we have seen, initiate the complicated forces, processes and expressions of sex.
This hormone also stimulates the body to heal wounds and burns, repair broken bones, generally replace any tissues that have been destroyed and, growth hormone stimulates the immune response. Growth hormone also maintains muscle tone and its presence generally slows the aging process.
Without this normal hormone for the activity of the sympathetic nervous system, there would be a disturbance of skin and circulatory reactions that would interfere with the normal heat loss. Suggestive evidence to support this view comes from the frequency with which the extremities are cyanotic or cold, the skin greasy, sweating profuse or absent, and so on.
Growth hormone might make a wonderful life-extension supplement; on it a middle-aged person might readily maintain the muscle tone of youth while slowing aging in general. Unfortunately, growth hormone cannot at this time be inexpensively synthesized and is still far too costly to be used therapeutically except to prevent dwarfism.
The reason why the somatic sexual character does not develop until the time of puberty, and develops again each breeding season in such cases as antlers, is that the original hypertrophy due to external stimulation occurred only when the testicular hormone was circulating in the blood.
Again, if it is the withdrawal of a hormone stimulus which changes the milk gland from growth to secretion, it cannot be the corpora lutea which are exclusively concerned even in Dasyurus, for they persist during lactation, while secretion begins shortly after parturition.
These products would act as a hormone on the gametocytes, stimulating the factors which in the next generation would control the development of the frontal bone and adjacent tissues.
How far Doncaster is right in holding that the soma is different in the two sexes is a question already mentioned, but it is obvious that in each individual the somatic sexual characters proper to its species are present potentially in its constitution by heredity in other words, as factors or determinants in the chromosomes of the zygote from which it was developed; but the normal development of such characters in the individual soma is either entirely dependent on the stimulus of the hormone of the gonad or is profoundly influenced by the presence or absence of that stimulus.
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