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To stop persistent oozing from soft tissues, Horsley successfully applied a portion of living vascular tissue, such as a fragment of muscle, which readily adheres to the oozing surface and yields elements that cause coagulation of the blood by thrombo-kinetic processes. When examined after two or three days the muscle has been found to be closely adherent and undergoing organisation.

Compare the red and white corpuscles with reference to size, shape, number, origin, and function. Name some use or purpose for each constituent of the blood. What constituents of the blood may be regarded as freight and what as agents for carrying this freight? After coagulation, what portions of the blood are found in the clot? What portions are found in the serum?

This milk it cannot digest because the emulsifying element, the fat, is not present in it in sufficient quantity in proportion to the coagulable matter. We must not forget either that the difference in coagulation holds also with respect to difference in the age and in the kind of animal.

The cause and the result of the treatment are often obscure. Bleeding, purging, and counter irritation, would be indicated to a certain extent, but the lowering system must not be carried too far. The medicine would probably be catechu, uva ursi, and opium. At times blood mingles with the urine, with or without coagulation. The cause and the source of it may or may not be determined.

Until, therefore, it is absolutely disproved, it must remain the simplest and most probable assumption that they are finally made of the same stuff, that the material molecule is some kind of knot or coagulation of ether." Fortnightly Review, June, 1875, p. 784.

A tangled mass of very curly black hair, matted with burs, dank with dew, and clotted with blood, fell partly over his forehead, on the edge of which, extending back into the hair, an ugly scalp wound was gaping, and, though apparently not just inflicted, was still bleeding slowly, as though reluctant to stop, in spite of the coagulation that had almost closed it.

The colorless corpuscles are to be seen among the red ones, but are much less numerous. The Coagulation of the Blood. Blood when shed from the living body is as fluid as water. But it soon becomes viscid, and flows less readily from one vessel to another. Soon the whole mass becomes a nearly solid jelly called a clot.

The formation of the clot and the separation of the serum is due almost entirely to the action of this substance. Fibrinogen is for this reason called the coagulable constituent of the blood. In the plasma the fibrinogen is in a liquid form; but during coagulation it changes into a white, stringy solid, called fibrin. This appears in the clot and is the cause of its formation.

There is a greater effect on the nerve-centres, but less swelling of the wound itself, and, whereas the blood of the rattlesnake's victim coagulates, the blood of the victim of an elapine snake that is, of one of the only poisonous American colubrines becomes watery and incapable of coagulation. Snakes are highly specialized in every way, including their prey.

The induration results from coagulation and partial organisation of the inflammatory effusion, and prevents the necessary contraction of the sore. The base of a callous ulcer lies at some distance below the level of the swollen, thickened, and white edges, and presents a glazed appearance, such granulations as are present being unhealthy and irregular.