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Updated: June 8, 2025
It is worth noting that all of our first experiments failed, despite the variety of culture media we employed urine, beer yeast water, meat water, etc. If this explanation of the contamination of our cultures was correct, we ought to find a pure culture of the septic vibrio in the heart's blood of an animal recently dead of septicemia.
There is only one possible hypothesis as to the existence of a virus in solution, and that is that such a substance, which was present in our experiment in nonfatal amounts, should be continuously furnished by the vibrio itself, during its growth in the body of the living animal.
These external diseases of the cereals are due to parasites, which may be either of an animal or vegetable nature. Among the animal parasites may be mentioned the weevil, vibrio tritici, which feeds upon the starch cells of the grain. Grain attacked by this parasite was at one time supposed to be injurious to health.
The mother died, and there was no autopsy. On May twenty-eighth, a rabbit was inoculated under the skin of the abdomen with five drops of the preceding culture of the pyogenic vibrio. The days following an enormous abscess formed which opened spontaneously on the fourth of June. An abundantly cheesy pus came from it. About the abscess there was extensive induration.
What is to be sought for in this instance is the proof that along with our vibrio there does not exist an independent virulence belonging to the surrounding fluids or solids, in short that the vibrio is not merely an epiphenomenon of the disease of which it is the obligatory accompaniment. What then do we see, in the results that I have just brought out?
"Or perhaps you did not read the 'Medley Pie' notice? That is a pity. Do take up the book again. Vibrio is a poor little tippling creature, but, as Mr Carlyle would say, he has an eye, and he is always lively." I did take up the book again, and read as demanded.
If we had found a wriggle, or a zigzag, or a shoot from one side to the other, in this last flask, what a scare there would have been, to be sure, in the schools of the prophets! Talk about your megatherium and your megalosaurus, what are these to the bacterium and the vibrio? These are the dreadful monsters of today.
After confinement, the pus that always naturally forms in the injured parts of the uterus instead of remaining pure becomes contaminated with microscopic organisms from outside, notably the organism in long chains and the pyogenic vibrio. These organisms pass into the peritoneal cavity through the tubes or by other channels, and some of them into the blood, probably by the lymphatics.
When the vibrio encounters an obstacle it turns, or after assuring itself by some visual effort or other that it cannot overcome it, it retraces its steps. The colpoda undoubted infusoria behave in an exactly similar manner.
Little Vibrio, who writes the playful notice in the 'Medley Pie, has a clever hit at Volvox in that passage about the steeplechase of imagination, where the loser wants to make it appear that the winner was only run away with. But if you did not notice Volvox's self-contradiction you would not see the point," added Vorticella, with rather a chilling intonation.
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