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Clinical Use of Vaccines. Vaccines should not be given while a patient is in a negative phase, as a certain amount of the opsonin in the blood is used up in neutralising the substances injected, and this may reduce the opsonic index to such an extent that the vaccines themselves become dangerous.

That immunity is a chemical reaction is no argument against the application of the law of natural selection or of association. The administration of vaccines becomes the adequate stimulus which awakens phylogenetic association of a chemical nature as a result of which immune bodies are produced.

I was educated medically in two of the colleges where medication is strongly advocated and well taught, and am a regular M. D. I have watched people who were treated by means of drugs and the biologic products, such as serums, vaccines and bacterines, which are now so popular, and I have watched many who have been treated by natural methods.

To counteract the general effect of toxins absorbed into the circulation, specific antitoxic sera are employed in certain forms of infection, such as diphtheria, streptococcal septicæmia, and tetanus. In other forms of infection, vaccines are employed to increase the opsonic power of the blood.

Although we are scientifically interested in the administration of specific treatments, antitoxins and vaccines; although we have a better understanding of food values, and order diets with more careful consideration of the exact needs of the individual, and although we are using various physical methods to promote elimination of toxins, poisons and products of metabolism, we have until lately forgotten the physical fact that one thirteenth of the weight of a normal adult is blood.

His beat was the respiratory tract and his treatment the last word in vaccines and serums. She held Darby back a little. "Must we go on feeling," she asked, "that anything could happen any minute? Or well, could Rush go back to the farm? Graham Stannard has gone to New York, I think, they're partners, you know, so he must be rather badly wanted. And this waiting is hard for him."

Preventive Treatment. The subject of preventive medicine becomes more important as our knowledge of the cause of disease advances. A knowledge of feeds, methods of feeding, care, sanitation and the use of such biological products as bacterins, vaccines and protective serums is of the greatest importance to the farmer and veterinarian.

None of these vaccines is so powerful, or so certain in its effects, as the diphtheria antitoxin.

Vaccines may be had recourse to in those of bacterial origin. Definition Pus Varieties Acute circumscribed abscess Acute suppuration in a wound Acute Suppuration in a mucous membrane Diffuse cellulitis and diffuse suppuration Whitlow Suppurative cellulitis in different situations Chronic suppuration Sinus, Fistula Constitutional manifestations of pyogenic infection Sapræmia Septicæmia Pyæmia.

Exactly how much harm such injections of unnecessary vaccines can produce in a patient is a question that has not been definitely decided. Theoretically an autogenous vaccine is the only vaccine which should be successful. The vaccine treatment of ulcerative endocarditis was not shown to be very successful by Dr. Int.