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This excessive flow, aside from actual local disease, is brought about by excessive muscular exercise during menstruation; by the use of all stimulants, whether alcoholic beverages or quinin; as well as by the thinness of the blood. When the flow is excessive, it must be considered a pathologic condition, which needs the physician's attention.
According to Lewin, there is mentioned in the case reported by Gauchet a symptom quite unique in the literature of quinin, viz., hemoptysis. Simon de Ronchard first noted the occurrence of several cases of hemoptysis following the administration of doses of eight grains daily. In the persons thus attacked the lungs and heart were healthy. Hemoptysis promptly ceased with the suspension of the drug.
"Lay up nothing!" cried Blake, and he clenched that determination by an outburst of blasphemous anger. But he secretly took great doses of quinin and drank much native liquor. He fought against a mental lassitude which he could not comprehend. Never before had that ample machinery of the body failed him in an emergency.
Quinin has not been shown to be of value, and salicylic acid is rarely of value unless the cause is rheumatism. Alcohol has been used in large doses, as it has been so frequently used in all septic processes. If the patient is unable to take nourishment in any amount, small doses of alcohol may be of benefit. It is probably of no other value.
It occurred to Ehrlich that if a substance could be devised which was poisonous for the germ and not for the patient it might be possible to prepare a specific for a given disease, acting as quinin does in malaria. By combining a poison with a dye it might be made to pick out the germs and leave the body unharmed.
The modern pharmacopeia does not possess any substance having a similar virtue, although quinin has been noticed to diminish the size of the spleen when engorged in malarial fevers. Strictly speaking, however, the facts are not analogous. Hippocrates advises a moxa of mushrooms applied over the spleen for melting or dissolving it.
He was content to wait until the fever grew, and the poisons of the blood narcotized the dulled brain into indifference, and then goaded it into delirium. Then, calmly equipping himself for his journey, he buried the repeating rifle and slipped away in the night, carrying with him Blake's quinin and revolver and pocket-filter. He traveled hurriedly, bearing southeast towards the San Juan.
The impression I make is one of incapability. For myself I am impossible, and for others more so." "Which has nothing to do with God," said Philip, in his tone a touch of distaste. Lawrence recognized it and became silent. Claire made him take the quinin and heated bricks for his feet. Philip went out to cut wood for the fire, leaving her alone with the sick man.
For the first time in his life he found his body shaken with fever and was compelled to use quinin in great quantities. The attacks of insects, of insects that flew, that crawled, that tunneled beneath the skin, turned life into a torment. His huge triple-terraced neck became raw with countless wounds. But he did not stop by the way.
Dauboeuf, Garraway, Hemming, Skinner, and Cobner mention roseola and scarlatiniform erythema after minute doses of quinin. In nearly all these cases the accompanying symptoms were different. Heusinger speaks of a lady who, after taking 1/2 grain of quinin, experienced headache, nausea, intense burning, and edema, together with nodular erythema on the eyelids, cheeks, and portion of the forehead.
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