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Updated: June 22, 2025
"The trouble with Miss Virginia," he added, deliberately, "seems to lie in one of what the scientists have lately designated the 'endocrine glands' in this case the pituitary. My X-ray pictures show that conclusively. "Let me explain for the benefit of the rest.
Arthur Keith, conservator of the Museum of the Royal College of Surgeons of England, was the first to apply the principle of endocrine differentiation to the problem of the color-lines the lines which have divided mankind crudely into the yellow, the red, the white and the brown, the Negro, the Mongol, the Caucasian, the copper tinted American.
Since the endocrine glands are so subtly sensitive and responsive to environment, and are at the same time so intimately concerned in the process of inheritance a law which sums up their influence upon resemblance and variation in animals there is no need to stress their importance for the practical science and art of good breeding, eugenics.
To sum up these relations of the viscera, the endocrines, the unconscious and the mind, it may be stated as a far-reaching generality for the understanding of human life: that character and conduct are expressions of the streams of energy arising in the vegetative apparatus, primarily endocrine determined at birth, and secondarily experience determined after the organism has learned to react as a whole, as consciousness.
War, pre-war, and post-war shocks have continued with their incessant pounding upon the reserves of energy. Under these conditions the adrenal personalities are bound to suffer. The other endocrine types suffer, too, but quite differently. Today, anti-adrenal, anti-religious ideas are epidemic.
No one can overrate this conception of migraine, for a number of men of genius have suffered from sick-headache and eye symptoms. As for epilepsy, the problem is more complex. One has to rule out first those who have organic destructive disease of the brain. But they are out of our field: genius predicates at least an intact brain. Of the others a number may be interpreted upon an endocrine basis.
All kinds of questions arise as soon as one attempts to consider the bearing of this underlying principle upon concrete situations. What happens, say, when a pituitocentric mates with a thyrocentric? Or when a pituitocentric marries a pituitocentric? Is there a reinforcement or a cancellation of the dominant endocrine?
There is a registration by the brain cells of the presence of the specific stimulus. Then there is communication by them with the endocrine organs. As a result, some of them are moved to further secretion, and others are paralyzed or weakened.
No one can deny, in the face of the multitude of evidence available, that internal secretion disturbances occur in the mother, which, when grave, offer in the infant gross proof of their significance, and therefore when slight must more subtly work upon it. Endocrine disturbances in infancy have been traced to endocrine disturbances in the mother during pregnancy.
Whether one will do one or the other may depend upon the relative predominance of the thyroid or of adrenal in the individual. In the distribution of fat beneath and throughout the skin all of the endocrine glands appear to have a voice.
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