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Updated: June 22, 2025
In persons afflicted with uncontrollable impulses, the inhibiting hormones may not be present in sufficient quantity. Feeble-mindedness, ranging from stupidity to imbecility, may also be a direct effect of insufficient endocrine supply to the brain cells.
The infantiloid constitution is one of arrested development, and may center around the arrested function in childhood or adolescence of any one or a number of endocrine glands. Yet the two may resemble one another pretty closely, at times. A cretin imitates the extreme grade of infantiloid constitution. The infantiloid is a sort of enlarged and lengthened child.
In view of all the possible mixtures, permutations and combinations of the endocrine glands, that may construct an individual, it is possible to conceive a million types of normals. For normality means harmony, the harmonious equilibrium between the hormones, which tends to continue itself, because it does no harm to itself.
In short, the history of his adventure is the history of his adrenals under stress and strain. It illustrates the mechanism of a typical endocrine neurosis. In the chapter on the glands of internal secretion as an interlocking directorate, certain generalities were stated as the laws of the government of the organism's life by them in association with the vegetative apparatus.
Further observations are necessary to confirm or disprove this hypothesis, but we feel inclined to accept it tentatively because it is plausible and consistent with the view that stupor is essentially a psychogenic type of reaction. Another physical anomaly, which is presumably of endocrine origin, is the suppression of the menses. This probably results from lowered nutrition.
What we know of the endocrine factors in heredity leads us to suppose that it is the mating of one marked endocrine insufficiency with another that is often responsible for the inherited tendency to feeble-mindedness and insanity. The effect of the hormone system upon the vegetative apparatus may create the more obscure insanities and quasi-insanities.
The direct action of the internal secretions upon the brain cells, producing a sort of hair trigger situation within them, may cause the explosive discharges from them which appear as overpowering impulses or uncontrollable conduct. The waves of feeling which precede them are unquestionably endocrine determined.
And the repression means a real interference with the release of energy, which remains bound up, tugging for room for expression as much as a spring tightly coiled in a box. In the production of that tension an endocrine has often been decisive.
Excessive stimulation or depression of an endocrine will disturb the whole chain of hormones, and the vegetative system, and their echoes in the psyche.
Besides, mental activity is accompanied by increased function of the ante-pituitary, if intellectual, or of the post-pituitary if emotional. Brain work then causes a temporary enlargement of the gland. If, now, the bone container of the endocrine is too small to permit of much swelling, the bone will be pressed against or even worn into.
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