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Updated: June 22, 2025
An endocrine organ will secrete at a certain rate. When it is stimulated excessively, it will eject extra amounts of its secretion. How long the period of excessive stimulation may last must depend upon the secretion potential or margin of reserve of the cells, varying from organ to organ, and from individual to individual.
And, as has been emphasized in preceding chapters, most neurasthenia rises upon a disturbed endocrine foundation, most often, an insufficiency of the adrenals. That is, a defect in the chain of co-operation, balance and compensation among the internal secretions is the basis for the weakness of the nervous system the term neurasthenia is supposed to explain, actually only names.
We have here an exquisite sample of the checks and compensations which make for a self-balancing of the whole endocrine system. The Dangerous Age is a phrase coined by a Scandinavian writer as a more dramatic euphemism for the time of life when sex function ceases, the climacteric. As a matter of fact, the age of adolescence is just as much of a dangerous age as the age of deliquescence.
He never appears to have asked himself what was behind the eye trouble. The evidence relating to Nietzsche's endocrine personality is derived from some of the data he collected, as well as from the two volume life of the philosopher written by his sister, and the other biographies of him extant.
Translated into endocrine terms, what happens may be pictured as a series of chemical events. When the activity of a ductless gland rises above a certain minimum, its hormones in the blood sensitize, as a photographic plate is sensitized, a group of brain cells, to respond to a message from the outside world, with a definite line of conduct.
There are certain terms for the glands of internal secretion which are used interchangeably. They are spoken of often as the endocrine glands and as the hormone producing glands. Endocrine is most convenient for it stands for both the gland and its secretion. Hormone is employed a good deal in the literature of the subject.
It was put forward as a fundamental revision of the theory, hitherto accepted, of the limitation of mind to the brain cells. We think and feel not alone with the brain, but with our muscles, our viscera, our vegetative nerves, and last but not least our endocrine organs. In short, we think and feel with each and every part of ourselves.
The general law followed by nature in her helterskelter way seems to be the production of the greatest number of hybrids and variations possible, whether for good or evil does not matter. Certain endocrine types appear to be specially attracted to others belonging to the same group. Thus thymus-centered types frequently marry.
In view of what has been said concerning the endocrine mechanism of the instincts and the vegetative apparatus, it could be predicted that a number of these nerve casualties of peace and war would be caused by an upset of the equilibrium between the glands of internal secretion. A study of war neuroses by the great Italian student of the endocrines, Pende, confirms this assumption.
A beginning of this study of endocrine inheritance, on the pathologic side, has been made. Some of these have been along Mendelian lines. If an endocrine abnormality like a goitre, or cretinism, or a dwarf or giant appear in a family as a sign of endocrine instability, other members of that family will very likely show internal secretion abnormalities.
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